Evidence map›Paper›PMID 34575919›Full record

ArticleInternational journal of molecular sciences2021

Mesoporous Aerogel Microparticles Injected into the Abdominal Cavity of Mice Accumulate in Parathymic Lymph Nodes.

Gábor Király, John Chinonso Egu, Zoltán Hargitai, Ilona Kovács, István Fábián, József Kalmár, Gábor Szemán-Nagy

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Particulate bioaerogels for respiratory drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gábor KirályDepartment of Molecular Biotechnology and Microbiology, University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.
John Chinonso EguMTA-DE ELKH Homogeneous Catalysis and Reaction Mechanisms Research Group, Department of Inorganic and Analytical Chemistry, University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.
Zoltán HargitaiDepartment of Pathology, Kenézy University Hospital, University of Debrecen, 2-28 Bartók Béla Street, H-4031 Debrecen, Hungary.
Ilona KovácsDepartment of Pathology, Kenézy University Hospital, University of Debrecen, 2-28 Bartók Béla Street, H-4031 Debrecen, Hungary.
István FábiánMTA-DE ELKH Homogeneous Catalysis and Reaction Mechanisms Research Group, Department of Inorganic and Analytical Chemistry, University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.ORCID 0000-0002-4467-2912
József KalmárMTA-DE ELKH Homogeneous Catalysis and Reaction Mechanisms Research Group, Department of Inorganic and Analytical Chemistry, University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.ORCID 0000-0002-2422-6106
Gábor Szemán-NagyDepartment of Molecular Biotechnology and Microbiology, University of Debrecen, Egyetem tér 1, H-4032 Debrecen, Hungary.ORCID 0000-0003-1906-0188
University of Debrecen · HU

Funding

Magyar Tudományos Akadémia János Bolyai Research ScholarshipNemzeti Kutatási Fejlesztési és Innovációs Hivatal OTKA FK-124571Nemzeti Kutatási Fejlesztési és Innovációs Hivatal OTKA K-124983
6 · The paper itself

Abstract

Mesoporous aerogel microparticles are promising drug delivery systems. However, their in vivo biodistribution pathways and health effects are unknown. Suspensions of fluorescein-labeled silica-gelatin hybrid aerogel microparticles were injected into the peritoneum (abdominal cavity) of healthy mice in concentrations of 52 and 104 mg kg

Indexed as

Abdominal CavityAnimalsBiocompatible MaterialsDrug CarriersDrug Delivery SystemsFluorescent Antibody TechniqueGelatinGelsImmunohistochemistryLymph NodesMiceNanoparticlesSilicon DioxideTissue DistributionBiocompatible MaterialsDrug CarriersGelatinGelsSilicon Dioxideaerogelbiocompatibilitybiodistributionfluoresceintoxicity

Identifiers

PMID34575919
PMCPMC8465913
OpenAlexW3196902718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.