Evidence map›Paper›PMID 34575895›Full record

ArticleInternational journal of molecular sciences2021

Unveiling the Metabolic Effects of Glycomacropeptide.

Maria João Pena, Raquel Costa, Ilda Rodrigues, Sandra Martins, João Tiago Guimarães, Ana Faria, Conceição Calhau, Júlio César Rocha, Nuno Borges

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Maria João PenaDepartamento de Biomedicina, Unidade de Bioquímica, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.ORCID 0000-0002-9138-6556
Raquel CostaDepartamento de Biomedicina, Unidade de Bioquímica, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.ORCID 0000-0002-9245-4565
Ilda RodriguesDepartamento de Biomedicina, Unidade de Bioquímica, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.
Sandra MartinsDepartment of Clinical Pathology, São João Hospital Centre, 4200-319 Porto, Portugal.ORCID 0000-0001-6813-314X
João Tiago GuimarãesDepartamento de Biomedicina, Unidade de Bioquímica, Faculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.ORCID 0000-0003-4836-6311
Ana FariaNutrition & Metabolism, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal.ORCID 0000-0002-5165-9513
Conceição CalhauNutrition & Metabolism, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal.ORCID 0000-0001-9567-3379
Júlio César RochaNutrition & Metabolism, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal.ORCID 0000-0002-4977-8345
Nuno BorgesCINTESIS-Centre for Health Technology and Services Research, 4200-450 Porto, Portugal.ORCID 0000-0001-6357-0615
Universidade do Porto · PTCentre for Health Technology and Services Research · PTHospital de São João · PTUnidade Local de Saúde de São José · PT

Funding

Norte2020 and Fundação para a Ciência e a Tecnologia (FCT) NORTE-08-5369-FSE-000018 and [UID/BIM/04293/2013]
6 · The paper itself

Abstract

For many years, the main nitrogen source for patients with phenylketonuria (PKU) was phenylalanine-free amino acid supplements. Recently, casein glycomacropeptide (GMP) supplements have been prescribed due to its functional and sensorial properties. Nevertheless, many doubts still persist about the metabolic effects of GMP compared to free amino acids (fAA) and intact proteins such as casein (CAS). We endeavour to compare, in rats, the metabolic effects of different nitrogen sources. Twenty-four male Wistar rats were fed equal energy density diets plus CAS (control,

Indexed as

Dietary SupplementsDiet TherapyAnimalsBiomarkersBody WeightCaseinsEatingGlucoseHumansImmunohistochemistryIntestinal MucosaPeptide FragmentsRatsBiomarkerscaseinomacropeptideCaseinsGlucosePeptide Fragmentsamino acidsGLP-1glycomacropeptideintact proteinmetabolismphenylketonuria

Identifiers

PMID34575895
PMCPMC8470927
OpenAlexW3198294380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.