Evidence map›Paper›PMID 34575859›Full record

ArticleInternational journal of molecular sciences2021

Nitrogen Functionalities of Amino-Functionalized Nitrogen-Doped Graphene Quantum Dots for Highly Efficient Enhancement of Antimicrobial Therapy to Eliminate Methicillin-Resistant

Wen-Shuo Kuo, Ping-Ching Wu, Chi-Yao Hung, Chia-Yuan Chang, Jiu-Yao Wang, Pei-Chi Chen, Miao-Hsi Hsieh, Sheng-Han Lin, Chan-Chi Chang, Yen-Sung Lin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Wen-Shuo KuoSchool of Chemistry and Materials Science, Nanjing University of Information Science and Technology, Nanjing 210044, China.
Ping-Ching WuDepartment of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan.
Chi-Yao HungDepartment of Physical Medicine and Rehabilitation, An Nan Hospital, China Medical University, Tainan 709, Taiwan.
Chia-Yuan ChangDepartment of Mechanical Engineering, National Cheng Kung University, Tainan 701, Taiwan.ORCID 0000-0003-0587-0868
Jiu-Yao WangAllergy & Clinical Immunology Research Center, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.ORCID 0000-0003-4540-9822
Pei-Chi ChenAllergy & Clinical Immunology Research Center, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.
Miao-Hsi HsiehAllergy & Clinical Immunology Research Center, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.
Sheng-Han LinDepartment of Anesthesiology, E-Da Hospital, Kaohsiung 824, Taiwan.
Chan-Chi ChangDepartment of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.
Yen-Sung LinDivision of Pulmonary and Critical Care Medicine, An Nan Hospital, China Medical University, Tainan 709, Taiwan.
China Medical University · TWNational Cheng Kung University Hospital · TWChung Hwa University of Medical Technology · TWE-Da Hospital · TW

Funding

An Nan Hospital, China Medical University, Taiwan ANHRF110-34; ANHRF110-35Ministry of Science and Technology, Taiwan MOST 109-2636-E-006-018-Research Start-Up Fund of Nanjing University of Information Science & Technology, China 2018r047State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, China CMEMR2021-B11
6 · The paper itself

Abstract

There is an urgent need for materials that can efficiently generate reactive oxygen species (ROS) and be used in photodynamic therapy (PDT) as two-photon imaging contrast probes. In this study, graphene quantum dots (GQDs) were subjected to amino group functionalization and nitrogen doping (amino-N-GQDs) via annealing and hydrothermal ammonia autoclave treatments. The synthesized dots could serve as a photosensitizer in PDT and generate more ROS than conventional GQDs under 60-s low-energy (fixed output power: 0.07 W·cm

Indexed as

Anti-Bacterial AgentsAntioxidantsContrast MediaDrug CarriersGraphiteMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsNitrogenQuantum DotsAnti-Bacterial AgentsAntioxidantsContrast MediaDrug CarriersGraphiteNitrogencontrast probegraphene quantum dot with nitrogen doping and amino group functionalizationmultidrug-resistant methicillin-resistant Staphylococcus aureusphotodynamic therapyreactive oxygen species

Identifiers

PMID34575859
PMCPMC8468865
OpenAlexW3197067368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.