Evidence map›Paper›PMID 34575837›Full record

ArticleInternational journal of molecular sciences2021

Evolving

Vinardas Kelpšas, Anna Leung, Claes von Wachenfeldt

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vinardas KelpšasDepartment of Biology, Lund University, Sölvegatan 35, SE-223 62 Lund, Sweden.ORCID 0000-0002-7969-349X
Anna LeungScientific Activities Division, European Spallation Source ERIC, P.O. Box 176, SE-221 00 Lund, Sweden.
Claes von WachenfeldtDepartment of Biology, Lund University, Sölvegatan 35, SE-223 62 Lund, Sweden.ORCID 0000-0001-8950-3218

Funding

Vetenskapsrådet 2019-05578_3
6 · The paper itself

Abstract

Labeling of proteins with deuterium (2H) is often necessary for structural biology techniques, such as neutron crystallography, NMR spectroscopy, and small-angle neutron scattering. Perdeuteration in which all protium (1H) atoms are replaced by deuterium is a costly process. Typically, expression hosts are grown in a defined medium with heavy water as the solvent, which is supplemented with a deuterated carbon source.

Indexed as

Adaptation, PhysiologicalCulture MediaDeuteriumEscherichia coliGene Expression Regulation, BacterialIsotope LabelingMagnetic Resonance SpectroscopyMutationPyruvic AcidRecombinant ProteinsSodiumCulture MediaDeuteriumPyruvic AcidRecombinant ProteinsSodiumadaptive experimental evolutiondeuterationisotope labellingneutron crystallography

Identifiers

PMID34575837
PMCPMC8465070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.