Evidence map›Paper›PMID 34575806›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

The Siderophore Transporters Sit1 and Sit2 Are Essential for Utilization of Ferrichrome-, Ferrioxamine- and Coprogen-Type Siderophores in

Mario Aguiar, Thomas Orasch, Matthias Misslinger, Anna-Maria Dietl, Fabio Gsaller, Hubertus Haas

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Iron acquisition strategies of the rock-inhabiting fungusApplied and environmental microbiology · 2026
    Article
  3. Article
  4. microLife · 2026
    Article
  5. Article
  6. Review
  7. Positron Emission Tomography Imaging ofACS infectious diseases · 2025
    Article
  8. Review
  9. Role of the putativeMicrobial cell (Graz, Austria) · 2025
    Article
  10. Article
  11. Article
  12. [ACS infectious diseases · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. TheFrontiers in microbiology · 2024
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mario AguiarInstitute of Molecular Biology/Biocenter, Medical University of Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0001-6075-3571
Thomas OraschInstitute of Molecular Biology/Biocenter, Medical University of Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0003-4653-4932
Matthias MisslingerInstitute of Molecular Biology/Biocenter, Medical University of Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0002-6380-700X
Anna-Maria DietlInstitute of Molecular Biology/Biocenter, Medical University of Innsbruck, A-6020 Innsbruck, Austria.
Fabio GsallerInstitute of Molecular Biology/Biocenter, Medical University of Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0002-9257-8648
Hubertus HaasInstitute of Molecular Biology/Biocenter, Medical University of Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0003-2472-9878
Innsbruck Medical University · AT

Funding

Austrian Science Fund W1253Euregio Science Fund IPN95
6 · The paper itself

Abstract

Siderophore-mediated acquisition of iron has been shown to be indispensable for the virulence of several fungal pathogens, the siderophore transporter Sit1 was found to mediate uptake of the novel antifungal drug VL-2397, and siderophores were shown to be useful as biomarkers as well as for imaging of fungal infections. However, siderophore uptake in filamentous fungi is poorly characterized. The opportunistic human pathogen

Indexed as

Aspergillus fumigatusfungiironmoldssiderophoretransporterxenosiderophores

Identifiers

PMID34575806
PMCPMC8470733
OpenAlexW3199523274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.