Evidence map›Paper›PMID 34575772›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Desferrioxamine B-Mediated Pre-Clinical In Vivo Imaging of Infection by the Mold Fungus

Matthias Misslinger, Milos Petrik, Joachim Pfister, Isabella Hubmann, Katerina Bendova, Clemens Decristoforo, Hubertus Haas

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Automated Production of [Pharmaceutics · 2024
    Article
  6. [ACS infectious diseases · 2024
    Article
  7. Article
  8. Iron chelators: as therapeutic agents in diseases.Annals of medicine and surgery (2012) · 2024
    Review
  9. Review
  10. Article
  11. Radiometal chelators for infection diagnostics.Frontiers in nuclear medicine · 2023
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Matthias MisslingerInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-6380-700X
Milos PetrikInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, 77900 Olomouc, Czech Republic.ORCID 0000-0003-1334-5916
Joachim PfisterDepartment of Nuclear Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-5357-126X
Isabella HubmannDepartment of Nuclear Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Katerina BendovaInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, 77900 Olomouc, Czech Republic.
Clemens DecristoforoDepartment of Nuclear Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-0566-4036
Hubertus HaasInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-2472-9878
Innsbruck Medical University · ATInstitute of Molecular and Translational Medicine · CZ

Funding

Austrian Science Fund FWF KLI 909Austrian Science Fund FWF P 30924
6 · The paper itself

Abstract

Fungal infections are a serious threat, especially for immunocompromised patients. Early and reliable diagnosis is crucial to treat such infections. The bacterially produced siderophore desferrioxamine B (DFO-B) is utilized by a variety of microorganisms for iron acquisition, while mammalian cells lack the uptake of DFO-B chelates. DFO-B is clinically approved for a variety of long-term chelation therapies. Recently, DFO-B-complexed gallium-68 ([

Indexed as

Aspergillus fumigatusdesferrioxamine Bgallium-68imaginginfectioninvasive pulmonary aspergillosisPETpHpositron emission tomographysiderophore

Identifiers

PMID34575772
PMCPMC8472378
OpenAlexW3196848233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.