ReviewJournal of personalized medicine2021
Current Trends in Advanced Alginate-Based Wound Dressings for Chronic Wounds.
Review in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 141 citations in OpenAlex.
- Engineering alginate hydrogels loaded with resveratrol as a dual platform for cancer therapy and wound regeneration.Discover nano · 2026Review
- Fish Collagen Hydrolysates in Wound Healing: A Patent Review.ACS pharmacology & translational science · 2026Review
- Biopolymer-Based Hydrogels for Wound Healing: Advances in Cellulose, Chitosan, Alginate, and Hyaluronic Acid from Design to Clinical Translation.Pharmaceuticals (Basel, Switzerland) · 2026Review
- A LECT2-elutingMaterials today. Bio · 2026Article
- Algae-Derived Bioactive Compounds as Platforms for Translational Biotechnology and Health Applications.Biotech (Basel (Switzerland)) · 2026Review
- Advancement in Sodium Alginate-Based Drug Delivery Systems: Applications and Future Prospects.AAPS PharmSciTech · 2026Review
- Sustainable ZnO/ZnGels (Basel, Switzerland) · 2026Article
- Optimal Wound pH and Related Factors in the Healing Process of Diabetes-Related Foot Ulcer: A Prospective Observational Study.Health science reports · 2026Article
- Recent Applications of Chitosan-Based Biomaterials as Wound Dressings.International journal of molecular sciences · 2026Review
- Functional roles and applications of polysaccharides in biomedical and food systems.Frontiers in bioengineering and biotechnology · 2026Review
- Biopolymer Hydrogel-Based Nanocomposites Functionalized with Natural Products for Wound Dressings: Translational Advances in Drug Design, Development, and Therapeutic Wound Care.Drug design, development and therapy · 2026Review
- Synthesis, Characterization, and Study of the Bioactivity of Nanosized Fe(III) and Cr(III) Coordination Polymers Based on Cross-Linked Sodium Alginate and Polyacrylic Acid Biopolymers.International journal of biomaterials · 2026Article
- Plasma-treated alginate hydrogels modulate porcine leukocyte activityFrontiers in immunology · 2026Article
- CMC-Based Injectable Hydrogels Crosslinked by Diels-Alder Chemistry for Wound Healing Applications.Gels (Basel, Switzerland) · 2025Article
- Alginate-based hydrogels loaded with human β-defensin-2 promote healing of MRSA-infected wounds in a diabetic model: a preclinical proof-of-concept study.Clinical and experimental medicine · 2025Article
- Dexketoprofen-Loaded Alginate-Grafted Poly(N-vinylcaprolactam)-Based Hydrogel for Wound Healing.International journal of molecular sciences · 2025Article
- Harnessing Manuka Honey: A Natural Remedy for Accelerated Burn Wound Healing in a Porcine Model.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Article
- Recent advances in the mechanisms, current treatment status, and application of multifunctional biomaterials for radiation-induced skin injury.Theranostics · 2025Review
- Natural biopolymer-based hydrogels: an advanced material for diabetic wound healing.Diabetology international · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic wounds represent a major public health issue, with an extremely high cost worldwide. In healthy individuals, the wound healing process takes place in different stages: inflammation, cell proliferation (fibroblasts and keratinocytes of the dermis), and finally remodeling of the extracellular matrix (equilibrium between metalloproteinases and their inhibitors). In chronic wounds, the chronic inflammation favors exudate persistence and bacterial film has a special importance in the dynamics of chronic inflammation in wounds that do not heal. Recent advances in biopolymer-based materials for wound healing highlight the performance of specific alginate forms. An ideal wound dressing should be adherent to the wound surface and not to the wound bed, it should also be non-antigenic, biocompatible, semi-permeable, biodegradable, elastic but resistant, and cost-effective. It has to give protection against bacterial, infectious, mechanical, and thermal agents, to modulate the level of wound moisture, and to entrap and deliver drugs or other molecules This paper explores the roles of alginates in advanced wound-dressing forms with a particular emphasis on hydrogels, nanofibers networks, 3D-scaffolds or sponges entrapping fibroblasts, keratinocytes, or drugs to be released on the wound-bed. The latest research reports are presented and supported with in vitro and in vivo studies from the current literature.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.