Evidence map›Paper›PMID 34575629›Full record

ArticleJournal of personalized medicine2021

Association of Breast Tumour Expression of Cannabinoid Receptors CBR1 and CBR2 with Prognostic Factors and Survival in Breast Cancer Patients.

Jessica Morin-Buote, Kaoutar Ennour-Idrissi, Éric Poirier, Julie Lemieux, Daniela Furrer, Anna Burguin, Francine Durocher, Caroline Diorio

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jessica Morin-BuoteDepartment of Social and Preventive Medicine, Faculty of Medicine, Laval University, Quebec City, QC G1V 0A6, Canada.
Kaoutar Ennour-IdrissiDepartment of Social and Preventive Medicine, Faculty of Medicine, Laval University, Quebec City, QC G1V 0A6, Canada.ORCID 0000-0002-0962-2020
Éric PoirierCHU de Québec-Université Laval Research Center, Quebec City, QC G1S 4L8, Canada.
Julie LemieuxCHU de Québec-Université Laval Research Center, Quebec City, QC G1S 4L8, Canada.
Daniela FurrerCHU de Québec-Université Laval Research Center, Quebec City, QC G1S 4L8, Canada.
Anna BurguinCHU de Québec-Université Laval Research Center, Quebec City, QC G1S 4L8, Canada.
Francine DurocherCHU de Québec-Université Laval Research Center, Quebec City, QC G1S 4L8, Canada.ORCID 0000-0001-8012-4641
Caroline DiorioDepartment of Social and Preventive Medicine, Faculty of Medicine, Laval University, Quebec City, QC G1V 0A6, Canada.ORCID 0000-0001-5355-7345
Université Laval · CAHôpital du Saint-Sacrement · CA

Funding

Fonds de Recherche du Québec - Santé Senior Investigator AwardTumor banking was supported by the Fondation du cancer du sein du Québec and the Banque de tissus et données of the Réseau de recherche sur le cancer of the Fond de recherche du Qué-bec-Santé (FRQS), NA
6 · The paper itself

Abstract

Cannabinoid receptors (CBR) are potential therapeutic targets for breast cancer. However, the role of CBR in breast cancer survival remains poorly understood. Data from a prospective cohort of 522 women diagnosed with invasive breast cancer between 2010 and 2012 were analysed. Clinical and pathological features were retrieved from electronic medical records. CBR expression was measured by immunohistochemistry. Adjusted partial Spearman correlations and multivariate Cox models were used to estimate associations with breast cancer prognostic factors and survival, respectively. The median follow-up was 92.0 months (range 7.0-114.0). CBR expression was heterogenous in tumours. Cytoplasmic expression of CBR1 was positively correlated with lymph node invasion (r

Indexed as

breast cancercannabinoid receptorcohort studyimmunohistochemistryprognostic factorssurvival

Identifiers

PMID34575629
PMCPMC8466730
OpenAlexW3198465645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.