Evidence map›Paper›PMID 34575621›Full record

ArticleJournal of personalized medicine2021

Poor Prognosis of Diffuse Large B-Cell Lymphoma with Hepatitis C Infection.

Yu-Fen Tsai, Yi-Chang Liu, Ching-I Yang, Tzer-Ming Chuang, Ya-Lun Ke, Tsung-Jang Yeh, Yuh-Ching Gau, Jeng-Shiun Du, Hui-Ching Wang, Shih-Feng Cho and 7 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Personalized Medicine in Epidemics.Journal of personalized medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Yu-Fen TsaiDepartment of Hematology & Oncology, E-Da Cancer Hospital, Kaohsiung 824, Taiwan.
Yi-Chang LiuDivision of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Ching-I YangDivision of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Tzer-Ming ChuangDivision of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.ORCID 0000-0003-1903-0042
Ya-Lun KeDivision of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Tsung-Jang YehDivision of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.ORCID 0000-0003-1634-2219
Yuh-Ching GauDivision of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Jeng-Shiun DuDivision of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.ORCID 0000-0002-7311-4979
Hui-Ching WangDivision of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.ORCID 0000-0002-8232-0387
Shih-Feng ChoDivision of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Chin-Mu HsuDivision of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.ORCID 0000-0002-3604-6022
Pey-Fang WuDivision of Hepatobiliary Ward, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Ching-I HuangFaculty of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chung-Feng HuangFaculty of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Ming-Lung YuFaculty of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0001-8145-1900
Chia-Yen DaiFaculty of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0003-2296-3054
Hui-Hua HsiaoDivision of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.ORCID 0000-0002-7381-1045
Kaohsiung Medical University · TWE-Da Hospital · TW

Funding

Kaohsiung Medical University Hospital KMUH108-8R24Kaohsiung Medical University Hospital KMUH109-9R19
6 · The paper itself

Abstract

backgroundHepatitis C virus (HCV) in diffuse large B-cell lymphoma (DLBCL) is associated with a higher prevalence and distinctive clinical characteristics and outcomes.

methodsA retrospective analysis of adult DLBCL patients from 2011 to 2015 was studied.

resultsA total of 206 adult DLBCL were enrolled with 22 (10.7%) HCV-positive patients. Compared to HCV-negative patients, the HCV-positive group had a poor performance status (

conclusionInferior survival of HCV-positive DLBCL was observed and associated with poor performance status, higher numbers of complications, and intolerance of treatment, leading to fewer therapy. Therefore, anti-HCV therapy, such as direct-acting antiviral agents, might benefit these patients in the future.

Indexed as

diffuse large B-cell lymphomafibrosishepatitis C virusliver toxicityperformance statussurvival

Identifiers

PMID34575621
PMCPMC8465128
OpenAlexW3198157033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.