Evidence map›Paper›PMID 34575617›Full record

ReviewJournal of personalized medicine2021

Endometrial SUSD2

David M Z B Hennes, Anna Rosamilia, Jerome A Werkmeister, Caroline E Gargett, Shayanti Mukherjee

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagyEuropean journal of histochemistry : EJH · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Prospects for use of bioengineered tissue from stem cells in gynecology.Acta obstetricia et gynecologica Scandinavica · 2023
    Article
  10. Article
  11. Article
  12. Endometrial Stem/Progenitor Cells: Prospects and Challenges.Journal of personalized medicine · 2022
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

David M Z B HennesThe Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.ORCID 0000-0002-1524-5970
Anna RosamiliaThe Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.
Jerome A WerkmeisterThe Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.
Caroline E GargettThe Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.ORCID 0000-0002-3590-2077
Shayanti MukherjeeThe Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.ORCID 0000-0001-9995-002X
Hudson Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular therapy is an emerging field in clinical and personalised medicine. Many adult mesenchymal stem/progenitor cells (MSC) or pluripotent derivatives are being assessed simultaneously in preclinical trials for their potential treatment applications in chronic and degenerative human diseases. Endometrial mesenchymal stem/progenitor cells (eMSC) have been identified as clonogenic cells that exist in unique perivascular niches within the uterine endometrium. Compared with MSC isolated from other tissue sources, such as bone marrow and adipose tissue, eMSC can be extracted through less invasive methods of tissue sampling, and they exhibit improvements in potency, proliferative capacity, and control of culture-induced differentiation. In this review, we summarize the potential cell therapy and tissue engineering applications of eMSC in pelvic organ prolapse (POP), emphasising their ability to exert angiogenic and strong immunomodulatory responses that improve tissue integration of novel surgical constructs for POP and promote vaginal tissue healing.

Indexed as

biomaterialsbioscaffoldscell cultureelectrospinningendometriummenstrual bloodMSCnanofiberperivascular MSCtissue engineering

Identifiers

PMID34575617
PMCPMC8471527
OpenAlexW3195475770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.