Evidence map›Paper›PMID 34575615›Full record

ReviewJournal of personalized medicine2021

Long COVID-19 Pulmonary Sequelae and Management Considerations.

Afroditi K Boutou, Andreas Asimakos, Eleni Kortianou, Ioannis Vogiatzis, Argyris Tzouvelekis

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Pulmonary manifestations of long COVID in Johannesburg, South Africa.Southern African journal of infectious diseases · 2025
    Article
  5. Article
  6. Article
  7. Observational
  8. Safety and Efficacy of Pulmonary Rehabilitation for Long COVID Patients Experiencing Long-Lasting Symptoms.International journal of environmental research and public health · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Effects of Aerobic Training in Patients with Subacute COVID-19: A Randomized Controlled Feasibility Trial.International journal of environmental research and public health · 2022
    Article
  17. Review
  18. Scoping review of rehabilitation care models for post COVID-19 condition.Bulletin of the World Health Organization · 2022
    Article
  19. [Organ-specific sequelae of COVID-19 in adults].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2022
    Review
  20. Global Trends and Research Hotspots in Long COVID: A Bibliometric Analysis.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Afroditi K BoutouDepartment of Respiratory Medicine, "G. Papanikolaou" Hospital, 57010 Thessaloniki, Greece.ORCID 0000-0001-7366-2038
Andreas AsimakosCritical Care Department and Pulmonary Unit, Evangelismos Hospital, Medical School, National and Kapodistrian University of Athens, 10676 Athens, Greece.
Eleni KortianouPhysiotherapy Department, University of Thessaly, 35100 Lamia, Greece.
Ioannis VogiatzisDepartment of Sport, Exercise and Rehabilitation, Northumbria University, Newcastle NE1 8ST, UK.ORCID 0000-0003-4830-7207
Argyris TzouvelekisDepartment of Respiratory Medicine, University Hospital of Patras, 26504 Patras, Greece.
General University Hospital of Patras · GRG. Papanikolaou General Hospital · GRNational and Kapodistrian University of Athens · GRNorthumbria University · GBUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human coronavirus 2019 disease (COVID-19) and the associated acute respiratory distress syndrome (ARDS) are responsible for the worst global health crisis of the last century. Similarly, to previous coronaviruses leading to past pandemics, including severe acute respiratory syndrome (SARS) and middle east respiratory syndrome (MERS), a growing body of evidence support that a substantial minority of patients surviving the acute phase of the disease present with long-term sequelae lasting for up to 6 months following acute infection. The clinical spectrum of these manifestations is widespread across multiple organs and consists of the long-COVID-19 syndrome. The aim of the current review is to summarize the current state of knowledge on the pulmonary manifestations of the long COVID-19 syndrome including clinical symptoms, parenchymal, and functional abnormalities, as well as highlight epidemiology, risk factors, and follow-up strategies for early identification and timely therapeutic interventions. The literature data on management considerations including the role of corticosteroids and antifibrotic treatment, as well as the therapeutic potential of a structured and personalized pulmonary rehabilitation program are detailed and discussed.

Indexed as

functional limitationparenchymal abnormalitiesPost-COVID sequelaerehabilitation

Identifiers

PMID34575615
PMCPMC8469288
OpenAlexW3193393853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.