Evidence map›Paper›PMID 34575604›Full record

ArticleJournal of personalized medicine2021

Asunción García-Sánchez, Miguel Estravís, Maria J Martin, Jacqueline Pérez-Pazos, Cristina Martín-García, María Gil-Melcón, Jacinto Ramos-González, Ibon Eguiluz-Gracia, Juan Carlos Triviño, María Isidoro-García and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. [Progress of allergic rhinitis research based on transcriptome sequencing].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024
    Review
  5. Biofilm in sino-nasal infectious diseases: the role nasal cytology in the diagnostic work up and therapeutic implications.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Asunción García-SánchezGrupo Alergología, Instituto de Investigación Biomédica de Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0002-9655-4918
Miguel EstravísGrupo Alergología, Instituto de Investigación Biomédica de Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0001-9788-4540
Maria J MartinGrupo Alergología, Instituto de Investigación Biomédica de Salamanca (IBSAL), 37007 Salamanca, Spain.
Jacqueline Pérez-PazosGrupo Alergología, Instituto de Investigación Biomédica de Salamanca (IBSAL), 37007 Salamanca, Spain.
Cristina Martín-GarcíaServicio de Inmunoalergia, Complejo Asistencial Universitario de Salamanca, 37007 Salamanca, Spain.
María Gil-MelcónServicio de Otorrinolaringología, Complejo Asistencial Universitario de Salamanca, 37007 Salamanca, Spain.
Jacinto Ramos-GonzálezServicio de Neumología, Complejo Asistencial Universitario de Salamanca, 37007 Salamanca, Spain.
Ibon Eguiluz-GraciaRed Cooperativa de Investigación en Salud-RETICS ARADyAL, 37007 Salamanca, Spain.ORCID 0000-0002-3774-931X
Juan Carlos TriviñoGrupo Bioinformática, Sistemas Genómicos, 46980 Paterna, Spain.ORCID 0000-0001-6752-8000
María Isidoro-GarcíaGrupo Alergología, Instituto de Investigación Biomédica de Salamanca (IBSAL), 37007 Salamanca, Spain.
Ignacio DávilaGrupo Alergología, Instituto de Investigación Biomédica de Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0001-8485-5513
Catalina SanzGrupo Alergología, Instituto de Investigación Biomédica de Salamanca (IBSAL), 37007 Salamanca, Spain.
Universidad de Salamanca · ESComplejo Hospitalario de Salamanca · ESHospital Regional Universitario de Málaga · ESInstituto de Investigación Biomédica de Salamanca · ESSistemas Genómicos · ES

Funding

Consejería de Educación, Junta de Castilla y León IES161P20Instituto de Salud Carlos III PI17/00818Instituto de Salud Carlos III PI20/00268Instituto de Salud Carlos III RETICS ARADyAL RD16/0006/0001Instituto de Salud Carlos III RETICS ARADyAL RD16/0006/0019Juan Rodés contract JR19/00029Junta de Castilla y León GRS2156/A/20Sociedad Española de Alergología e Inmunología Clinica BECA_Davila19
6 · The paper itself

Abstract

backgroundPrecision medicine is a promising strategy to identify biomarkers, stratify asthmatic patients according to different endotypes, and match them with the appropriate therapy. This proof-of-concept study aimed to investigate whether gene expression in peripheral blood could provide a valuable noninvasive approach for the molecular phenotyping of asthma.

methodsWe performed whole-transcriptome RNA sequencing on peripheral blood of 30 non-atopic non-asthmatic controls and 30 asthmatic patients. A quantitative PCR (qPCR) validation study of

results

conclusionsWe found that

Indexed as

aspirin exacerbated respiratory disease (AERD)asthmabiomarkerchronic rhinosinusitis with nasal polyps (CRSwNP)gene expressionPTGDR2

Identifiers

PMID34575604
PMCPMC8468563
OpenAlexW3193692188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.