Evidence map›Paper›PMID 34575570›Full record

ArticlePharmaceutics2021

Synthetic Antiferromagnetic Gold Nanoparticles as Bimodal Contrast Agents in MRI and CT-An Experimental In Vitro and In Vivo Study.

Antoine D'Hollander, Ruben Van Roosbroeck, Jesse Trekker, Tim Stakenborg, Tom Dresselaers, Greetje Vande Velde, Tom Struys, Ivo Lambrichts, Jeroen Lammertyn, Liesbet Lagae and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Antoine D'HollanderBiomedical MRI Unit, Department of Imaging and Pathology, KU Leuven, O&N 1, Herestraat 49, 3000 Leuven, Belgium.
Ruben Van RoosbroeckDepartment of Life Science Technology, IMEC, Kapeldreef 75, 3001 Leuven, Belgium.ORCID 0000-0002-4323-9658
Jesse TrekkerBiomedical MRI Unit, Department of Imaging and Pathology, KU Leuven, O&N 1, Herestraat 49, 3000 Leuven, Belgium.
Tim StakenborgDepartment of Life Science Technology, IMEC, Kapeldreef 75, 3001 Leuven, Belgium.ORCID 0000-0001-9878-9078
Tom DresselaersBiomedical MRI Unit, Department of Imaging and Pathology, KU Leuven, O&N 1, Herestraat 49, 3000 Leuven, Belgium.
Greetje Vande VeldeBiomedical MRI Unit, Department of Imaging and Pathology, KU Leuven, O&N 1, Herestraat 49, 3000 Leuven, Belgium.ORCID 0000-0002-5633-3993
Tom StruysLab of Histology, Biomedical Research Institute, Hasselt University, Agora Laan Gebouw C, 3590 Diepenbeek, Belgium.
Ivo LambrichtsLab of Histology, Biomedical Research Institute, Hasselt University, Agora Laan Gebouw C, 3590 Diepenbeek, Belgium.ORCID 0000-0001-7520-0021
Jeroen LammertynDivision of Mechatronics, Department of Biosystems, Biostatistics and Sensors, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0001-8143-6794
Liesbet LagaeDepartment of Life Science Technology, IMEC, Kapeldreef 75, 3001 Leuven, Belgium.
Uwe HimmelreichBiomedical MRI Unit, Department of Imaging and Pathology, KU Leuven, O&N 1, Herestraat 49, 3000 Leuven, Belgium.ORCID 0000-0002-2060-8895
IMEC · BEKU Leuven · BEHasselt University · BE

Funding

Agentschap voor Innovatie door Wetenschap en Technologie IWT 080017 (SBO Imagine)Agentschap voor Innovatie door Wetenschap en Technologie IWT 140061 (SBO NanoCoMIT)Horizon 2020 H2020-FET-OPEN-766456 (AMPHORA)Horizon 2020 H2020-NMP-2015-686009 (PANA)Onderzoeksraad, KU Leuven C14/20/095Seventh Framework Programme FP7-NMP-2008-228933
6 · The paper itself

Abstract

The use of multimodal contrast agents can potentially overcome the intrinsic limitations of individual imaging methods. We have validated synthetic antiferromagnetic nanoparticles (SAF-NPs) as bimodal contrast agents for in vitro cell labeling and in vivo cell tracking using magnetic resonance imaging (MRI) and computed tomography (CT). SAF-NP-labeled cells showed high contrast in MRI phantom studies (r

Indexed as

antiferromagnetic nanoparticlesbimodal contrast agentcomputed tomographyCTgold nanoparticlesmagnetic resonance imagingMRItop down synthesis

Identifiers

PMID34575570
PMCPMC8472775
OpenAlexW3201248760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.