ArticlePharmaceutics2021
Dual Cross-Linked Chitosan/PVA Hydrogels Containing Silver Nanoparticles with Antimicrobial Properties.
Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 93 citations in OpenAlex.
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- Comparative Effects of ZnO, MgO, and CaO Nanoparticles in 3D-Printed Chitosan-Agarose Scaffolds on Antibacterial and Osteogenic Outcomes.Macromolecular bioscience · 2025Article
- In Situ Formation of Silver Nanoparticles-Containing Gallic Acid-Conjugated Chitosan Hydrogels as Antimicrobial Tissue Adhesive Materials.Biomimetics (Basel, Switzerland) · 2025Article
- Enhancement of the structure and linear/nonlinear optical properties of PVA/chitosan/Ag nanocomposites for optoelectronic and antibacterial applications.Scientific reports · 2025Article
- Biodegradable chitosan/PVA-based hydrogel incorporating green synthesized silver nanoparticles for wound healing applications.BMC chemistry · 2025Article
- One-Pot Synthesis of Gelatin/Gum Arabic Hydrogels Embedding Silver Nanoparticles as Antibacterial Materials.Gels (Basel, Switzerland) · 2025Article
- Poly(vinyl alcohol)/Gentamicin and Poly(vinyl alcohol)/Chitosan/Gentamicin: Promising Materials for Rapid Burn Wound Healing.Gels (Basel, Switzerland) · 2025Article
- Effective PVC-PVA@Chitosan quantum dot membrane for sustainable water purification.RSC advances · 2025Article
- Synthesis of chitosan/PVA/copper oxide nanocomposite using Anacardium occidentale extract and evaluating its antioxidant, antibacterial, anti-inflammatory and cytotoxic activities.Scientific reports · 2025Article
- Hydrogel applications: a promising frontier in pneumonia therapy.Frontiers in bioengineering and biotechnology · 2025Review
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- Polysaccharide-Based Hydrogels for Advanced Biomedical Engineering Applications.ACS polymers Au · 2024Review
- Classification, synthesis, characterization, and applications of metal nanoparticle-containing hybrid microgels: a comprehensive review.RSC advances · 2024Review
- Antimicrobial Hydrogels Based on Cationic Curdlan Derivatives for Biomedical Applications.Gels (Basel, Switzerland) · 2024Article
- A review on Ag nanoparticles fabricated in microgels.RSC advances · 2024Review
- Recent Applications of Chitosan and Its Derivatives in Antibacterial, Anticancer, Wound Healing, and Tissue Engineering Fields.Polymers · 2024Review
- Pharmaceutical Applications of Biomass Polymers: Review of Current Research and Perspectives.Polymers · 2024Review
- Chitosan-Oxidized Pullulan Hydrogels Loaded with Essential Clove Oil: Synthesis, Characterization, Antioxidant and Antimicrobial Properties.Gels (Basel, Switzerland) · 2024Article
- Chitosan-Based Scaffolds Incorporated with Silver Nanoparticles for the Treatment of Infected Wounds.Pharmaceutics · 2024Review
- Degradable Polymeric Bio(nano)materials and Their Biomedical Applications: A Comprehensive Overview and Recent Updates.Polymers · 2024Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Stable chitosan/PVA-based hydrogels were obtained by combining covalent and physical cross-linking methods. As covalent cross-linkers, epoxy agents with different chain lengths were used, while freeze-thaw cycles were applied for additional physical cross-linking. The chemical structure of the hydrogel was examined by FTIR spectroscopy whereas the morphology was analyzed by SEM, showing well-defined pores with dimensions of around 50 μm in diameter. It was proved that gel fraction and the network morphology were deeply influenced by the synthesis conditions. Chitosan/PVA hydrogel showed a relative high swelling rate, reaching equilibrium in the first hour. The values obtained for the elastic modulus were relatively low (3-30 kPa); as a result, these hydrogels are soft and very flexible, and are ideal candidates for medical applications as wound or oral dressings. In addition, the natural antimicrobial activity of chitosan was enhanced by in situ generation of silver nanoparticles (AgNPs) under UV irradiation. The total amount of Ag from hydrogel was determined by elemental analyses and its crystalline state was confirmed by XRD. The CS/PVA hydrogels entrapped with AgNPs exhibited high inhibitory activity against
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.