Evidence map›Paper›PMID 34575496›Full record

ArticlePharmaceutics2021

Co-Delivery of Curcumin and Bioperine via PLGA Nanoparticles to Prevent Atherosclerotic Foam Cell Formation.

Sindhu C Pillai, Ankita Borah, Minh Nguyen Tuyet Le, Hiroaki Kawano, Kouichi Hasegawa, D Sakthi Kumar

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
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  12. How Advanced Is Nanomedicine for Atherosclerosis?International journal of nanomedicine · 2025
    Review
  13. Review
  14. Current State of Scientific Knowledge on Curcumin Encapsulation and Applications.Recent advances in food, nutrition & agriculture · 2025
    Review
  15. Nano Delivery System for Atherosclerosis.Journal of functional biomaterials · 2024
    Review
  16. Article
  17. Review
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sindhu C PillaiBio-Nano Electronics Research Centre, Graduate School of Interdisciplinary Science, Toyo University, 2100, Kujirai, Saitama, Kawagoe 350-8585, Japan.
Ankita BorahBio-Nano Electronics Research Centre, Graduate School of Interdisciplinary Science, Toyo University, 2100, Kujirai, Saitama, Kawagoe 350-8585, Japan.
Minh Nguyen Tuyet LeInstitute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto 606-8302, Japan.
Hiroaki KawanoInstitute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto 606-8302, Japan.
Kouichi HasegawaInstitute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto 606-8302, Japan.ORCID 0000-0001-5947-5471
D Sakthi KumarBio-Nano Electronics Research Centre, Graduate School of Interdisciplinary Science, Toyo University, 2100, Kujirai, Saitama, Kawagoe 350-8585, Japan.
Kyoto University · JPToyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholesterol-rich arterial plaques characterize atherosclerosis, a significant cause of heart disease. Nutraceuticals have received attention over the years, demonstrating potential benefits towards treating and preventing cardiovascular diseases (CVD), including atherosclerosis. Curcumin, a potent polyphenol present in

Indexed as

atherosclerosisbioperinecurcuminfoam cellsmacrophagesPLGA nanoparticle

Identifiers

PMID34575496
PMCPMC8468720
OpenAlexW3198503746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.