Evidence map›Paper›PMID 34575492›Full record

ArticlePharmaceutics2021

Sustained-Release and pH-Adjusted Alginate Microspheres-Encapsulated Doxorubicin Inhibit the Viabilities in Hepatocellular Carcinoma-Derived Cells.

Cheng-Tang Pan, Ruei-Siang Yu, Chih-Jung Yang, Lih-Ren Chen, Zhi-Hong Wen, Nai-Yu Chen, Hsin-You Ou, Chun-Yen Yu, Yow-Ling Shiue

Abstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cheng-Tang PanInstitute of Precision Medicine, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.
Ruei-Siang YuDepartment of Pharmacy, Kaohsiung Armed Forces General Hospital, Kaohsiung 80424, Taiwan.ORCID 0000-0001-6950-3923
Chih-Jung YangDepartment of Mechanical and Electro-Mechanical Engineering, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.
Lih-Ren ChenDivision of Physiology, Livestock Research Institute, Council of Agriculture, Tainan 71246, Taiwan.
Zhi-Hong WenDepartment of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.ORCID 0000-0003-4411-044X
Nai-Yu ChenInstitute of Precision Medicine, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.
Hsin-You OuLiver Transplantation Program and Departments of Diagnostic Radiology and Surgery, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.ORCID 0000-0002-6992-6253
Chun-Yen YuLiver Transplantation Program and Departments of Diagnostic Radiology and Surgery, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.
Yow-Ling ShiueInstitute of Precision Medicine, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.ORCID 0000-0003-0798-5028

Funding

Kaohsiung Armed Forces General Hospital KAFGH_A_110006Kaohsiung Chang Gung Memorial Hospital CMRPG8K0201
6 · The paper itself

Abstract

The objective of this study aimed to develop biodegradable calcium alginate microspheres carrying doxorubicin (Dox) at the micrometer-scale for sustained release and the capacity of pH regulatory for transarterial chemoembolization. Ultrasonic atomization and CaCl

Indexed as

DoxmicrospherepH-adjustedsodium alginateultrasonic atomization

Identifiers

PMID34575492
PMCPMC8471522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.