Evidence map›Paper›PMID 34575458›Full record

ArticlePharmaceutics2021

Dual Emissive Ir(III) Complexes for Photodynamic Therapy and Bioimaging.

Marta Redrado, Andrea Benedi, Isabel Marzo, M Concepción Gimeno, Vanesa Fernández-Moreira

Abstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Progress of Nanomaterials in Photodynamic Therapy Against Tumor.Frontiers in bioengineering and biotechnology · 2022
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marta RedradoDepartamento de Química Inorgánica, Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), CSIC-Universidad de Zaragoza, 50009 Zaragoza, Spain.
Andrea BenediDepartamento de Bioquímica y Biología Celular, Universidad de Zaragoza-CSIC, 50009 Zaragoza, Spain.ORCID 0000-0002-8581-8260
Isabel MarzoDepartamento de Bioquímica y Biología Celular, Universidad de Zaragoza-CSIC, 50009 Zaragoza, Spain.ORCID 0000-0002-2315-9079
M Concepción GimenoDepartamento de Química Inorgánica, Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), CSIC-Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0003-0553-0695
Vanesa Fernández-MoreiraDepartamento de Química Inorgánica, Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), CSIC-Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-1218-7218

Funding

Agencia Estatal de Investigación PID2019-104379RB-C21Agencia Estatal de Investigación RED2018-102471-TAgencia Estatal de Investigación RTI2018-097836-J-I00Agencia Estatal de Investigación RYC2018-025872-IGobierno de Aragón E07_20R
6 · The paper itself

Abstract

Photodynamic therapy (PDT) is a cancer treatment still bearing enormous prospects of improvement. Within the toolbox of PDT, developing photosensitizers (PSs) that can specifically reach tumor cells and promote the generation of high concentration of reactive oxygen species (ROS) is a constant research goal. Mitochondria is known as a highly appealing target for PSs, thus being able to assess the biodistribution of the PSs prior to its light activation would be crucial for therapeutic maximization. Bifunctional Ir(III) complexes of the type [Ir(C^N)

Indexed as

cytotoxicitydual emiterfluorescence microscopyiridiummitochondriaoptical propertiesphotodynamic therapy

Identifiers

PMID34575458
PMCPMC8472790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.