Evidence map›Paper›PMID 34575361›Full record

ReviewJournal of clinical medicine2021

Reticulocyte and Erythrocyte Hemoglobin Parameters for Iron Deficiency and Anemia Diagnostics in Patient Blood Management. A Narrative Review.

Christian Hoenemann, Norbert Ostendorf, Alexander Zarbock, Dietrich Doll, Olaf Hagemann, Mathias Zimmermann, Markus Luedi

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Christian HoenemannMarienhospital Vechta, Abteilung für Anästhesiologie und Operative Intensivmedizin, Marienstrasse 6-8, 49377 Vechta, Germany.
Norbert OstendorfSt. Franziskus-Hospital Münster, 48145 Münster, Germany.ORCID 0000-0002-4070-0840
Alexander ZarbockDepartment Westfälische, Wilhelms, Universität Münster, 48149 Münster, Germany.
Dietrich DollMarienhospital Vechta, Abteilung für Anästhesiologie und Operative Intensivmedizin, Marienstrasse 6-8, 49377 Vechta, Germany.
Olaf HagemannMarienhospital Vechta, Abteilung für Anästhesiologie und Operative Intensivmedizin, Marienstrasse 6-8, 49377 Vechta, Germany.
Mathias ZimmermannDRK Kliniken Berlin, Institut für Labormedizin, 14050 Berlin, Germany.
Markus LuediDepartment of Anaesthesiology, Inselspital, Bern University Hospital, University of Bern, 3012 Bern, Switzerland.ORCID 0000-0002-9049-2584
DRK Kliniken Berlin · DESt. Franziskus Hospital · DEUniversity of Bern · CHUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anemia, iron deficiency and other hematinic deficiencies are a major cause of perioperative transfusion needs and are associated with increased morbidity and mortality. Anemia can be caused either by decreased production of hemoglobin or red blood cells or by increased consumption and blood loss. Decreased production can involve anything from erythropoietin or vitamin B12 insufficiency to absolute or functional lack of iron. Thus, to achieve the goal of patient blood management, anemia must be addressed by addressing its causes. The traditional parameters to diagnose anemia, despite offering elaborate options, are not ideally suited to giving a simple overview of the causes of anemia, e.g., iron status for erythropoiesis, especially during the acute phase of inflammation, acute blood loss or iron deficiency. Reticulocyte hemoglobin can thus help to uncover the cause of the anemia and to identify the main factors inhibiting erythropoiesis. Regardless of the cause of anemia, reticulocyte hemoglobin can also quickly track the success of therapy and, together with the regular full blood count it is measured alongside, help in clearing the patient for surgery.

Indexed as

anemiaanemia of inflammation (ACD, anemia of chronic decease)hospital acquired anemiairon deficiencypatient blood managementreticulocyte hemoglobin (Ret He)

Identifiers

PMID34575361
PMCPMC8470754
OpenAlexW3198978731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.