Evidence map›Paper›PMID 34575355›Full record

ArticleJournal of clinical medicine2021

The Role of IONM in Reducing the Occurrence of Shoulder Syndrome Following Lateral Neck Dissection for Thyroid Cancer.

Andrea Polistena, Monia Ranalli, Stefano Avenia, Roberta Lucchini, Alessandro Sanguinetti, Sergio Galasse, Fabio Rondelli, Jacopo Vannucci, Renato Patrone, Nunzio Velotti and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Intraoperative Spinal Accessory Nerve Monitoring During Neck Dissection Surgery as a Predictor for Shoulder Dysfunction.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Andrea PolistenaEndocrine Surgery, Santa Maria University Hospital, Perugia University, 05100 Terni, Italy.ORCID 0000-0002-1319-1147
Monia RanalliDepartment of Statistical Sciences, Sapienza University of Rome, 00185 Rome, Italy.
Stefano AveniaResidency Programme in General Surgery, Faculty of Medicine and Surgery, University of Perugia, 06123 Perugia, Italy.
Roberta LucchiniEndocrine Surgery, Santa Maria University Hospital, Perugia University, 05100 Terni, Italy.
Alessandro SanguinettiEndocrine Surgery, Santa Maria University Hospital, Perugia University, 05100 Terni, Italy.
Sergio GalasseEndocrine Surgery, Santa Maria University Hospital, Perugia University, 05100 Terni, Italy.
Fabio RondelliEndocrine Surgery, Santa Maria University Hospital, Perugia University, 05100 Terni, Italy.
Jacopo VannucciDepartment of Surgery Paride Stefanini, Thoracic Surgery, Sapienza University of Rome, University Hospital Policlinico Umberto I, 00161 Rome, Italy.
Renato PatronePhD ICHT, University of Naples Federico II, 80131 Napoli, Italy.ORCID 0000-0002-6969-4157
Nunzio VelottiDepartment of Advanced Biomedical Science, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-3478-6270
Giovanni ConzoDepartment of Traslational Medical Sciences, Division of General and Oncologic Surgery, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.
Nicola AveniaEndocrine Surgery, Santa Maria University Hospital, Perugia University, 05100 Terni, Italy.
University of Perugia · ITUniversity of Naples Federico II · ITPoliclinico Umberto I · ITSapienza University of Rome · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lateral neck dissection (LND) leads to a significant morbidity involving accessory nerve injury. Modified radical neck dissection (MRND) aims at preservation of the accessory nerve, but patients often present with negative functional outcomes after surgery. The role of neuromonitoring (IONM) in the prevention of shoulder syndrome has not yet been defined in comparison to nerve visualization only. We retrospectively analyzed 56 thyroid cancer patients who underwent MRND over a period of six years (2015-2020) in a high-volume institution. Demographic variables, type of surgical procedure, removed lymph nodes and the metastatic node ratio, pathology, adoption of IONM and shoulder functional outcome were investigated. The mean number of lymph nodes removed was 15.61, with a metastatic node ratio of 0.2745. IONM was used in 41.07% of patients, with a prevalence of 68% in the period 2017-2020. IONM adoption showed an effect on post-operative shoulder function. There were no effects in 89.29% of cases, and temporary and permanent effects in 8.93% and 1.79%, respectively. Confidence intervals and two-sample tests for equality of proportions were used when applicable. Expertise in high-volume centres and IONM during MRND seem to be correlated with a reduced prevalence of accessory nerve lesions and limited functional impairments. These results need to be confirmed by larger prospective randomized controlled trials.

Indexed as

accessory nerveIONMneck dissectionshoulder syndromethyroid cancer

Identifiers

PMID34575355
PMCPMC8469441
OpenAlexW3201513157

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.