Evidence map›Paper›PMID 34575349›Full record

ArticleJournal of clinical medicine2021

Arterial Stiffness Assessment Using the Arteriograph in Patients with Moderate-Severe OSA and Metabolic Syndrome-A Pilot Study.

Ioana Mădălina Zota, Cristian Stătescu, Radu Andy Sascău, Mihai Roca, Larisa Anghel, Ovidiu Mitu, Cristina Mihaela Ghiciuc, Daniela Boisteanu, Razvan Anghel, Sebastian Romica Cozma and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07180147 (Arlington Longitudinal Optimal Healthy Aging Study), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07180147 active not recruitingnot on this mapstarted 2025, after this paper: background citation

Arlington Longitudinal Optimal Healthy Aging Study (ALOHA)

TypeobservationalSponsorMarymount UniversityRan2025 to 2031Enrolled500ConditionsAlzheimer Disease (AD), Cardio Vascular Disease, Mild Cognitive Impairment (MCI), Frailty Syndrome
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  4. Article
  5. Distinct Features of Vascular Diseases in COVID-19.Journal of inflammation research · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Ioana Mădălina ZotaDepartment of Medical Specialties (I), Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iași, 700115 Iasi, Romania.ORCID 0000-0003-4053-4130
Cristian StătescuDepartment of Medical Specialties (I), Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iași, 700115 Iasi, Romania.
Radu Andy SascăuDepartment of Medical Specialties (I), Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iași, 700115 Iasi, Romania.
Mihai RocaDepartment of Medical Specialties (I), Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iași, 700115 Iasi, Romania.
Larisa AnghelDepartment of Medical Specialties (I), Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iași, 700115 Iasi, Romania.
Ovidiu MituDepartment of Medical Specialties (I), Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iași, 700115 Iasi, Romania.ORCID 0000-0002-9438-8565
Cristina Mihaela GhiciucDepartment of Morpho-Functional Sciences (II), Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iași, 700115 Iasi, Romania.ORCID 0000-0003-1791-0425
Daniela BoisteanuDepartment of Medical Specialties (III), Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iași, 700115 Iasi, Romania.
Razvan AnghelDepartment of Medical Specialties (I), Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iași, 700115 Iasi, Romania.
Sebastian Romica CozmaDepartment of Surgery (II), Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iași, 700115 Iasi, Romania.ORCID 0000-0002-3768-6232
Lucia Corina Dima-CozmaDepartment of Medical Specialties (I), Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iași, 700115 Iasi, Romania.
Florin MituDepartment of Medical Specialties (I), Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iași, 700115 Iasi, Romania.
Grigore T. Popa University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBoth obstructive sleep apnea (OSA) and metabolic syndrome (MS) promote arterial stiffening. As a basis for this study, we presumed that arterial stiffness could be assessed using the Arteriograph (TensioMed, Budapest, Hungary) to detect early modifications induced by continuous positive airway therapy (CPAP) in reversing this detrimental vascular remodeling. Arterial stiffness is increasingly acknowledged as a major cardiovascular risk factor and a marker of subclinical hypertension-mediated organ damage. The aim of this pilot study was to evaluate the arterial stiffness changes in patients with moderate-severe OSA and MS after short-term CPAP use.

methodsWe performed a prospective study that included patients with moderate-severe OSA and MS who had not undergone previous CPAP therapy. All subjects underwent clinical examination and arterial stiffness assessment using the oscillometric technique with Arteriograph (TensioMed, Budapest, Hungary) detection before and after 8-week CPAP therapy.

results39 patients with moderate-severe OSA were included. Eight weeks of CPAP therapy significantly improved central systolic blood pressure (Δ = -11.4 mmHg,

conclusionsArterial stiffness was improved only among CPAP adherent patients and could be detected using the Arteriograph (TensioMed, Budapest, Hungary), which involves a noninvasive procedure that is easy to implement for the clinical evaluation of arterial stiffness.

Indexed as

adherencearterial stiffnessArteriographcontinuous positive airway pressure (CPAP)metabolic syndrome (MS)obstructive sleep apnea (OSA)

Identifiers

PMID34575349
PMCPMC8471747
OpenAlexW3200146880

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.