Evidence map›Paper›PMID 34575174›Full record

ArticleJournal of clinical medicine2021

Impact of the Vaginal and Endometrial Microbiome Pattern on Assisted Reproduction Outcomes.

María Del Carmen Diaz-Martínez, Andrea Bernabeu, Belén Lledó, Concepción Carratalá-Munuera, Jose A Quesada, Francisca M Lozano, Vicente Ruiz, Ruth Morales, Joaquín Llácer, Jorge Ten and 6 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  12. Article
  13. All Properties of Infertility Microbiome in a Review Article.Journal of clinical laboratory analysis · 2025
    Review
  14. Flagellin in blood andiScience · 2025
    Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

María Del Carmen Diaz-MartínezInstituto Bernabeu Reproductive Medicine, 03016 Alicante, Spain.
Andrea BernabeuInstituto Bernabeu Reproductive Medicine, 03016 Alicante, Spain.
Belén LledóMolecular Laboratory, Instituto Bernabeu Biotech, 03016 Alicante, Spain.ORCID 0000-0002-3583-7893
Concepción Carratalá-MunueraClinical Medicine Department, School of Medicine, University Miguel Hernández de Elche, 03550 Alicante, Spain.ORCID 0000-0002-1303-6294
Jose A QuesadaClinical Medicine Department, School of Medicine, University Miguel Hernández de Elche, 03550 Alicante, Spain.
Francisca M LozanoMolecular Laboratory, Instituto Bernabeu Biotech, 03016 Alicante, Spain.
Vicente RuizInstituto Bernabeu Reproductive Medicine, 03016 Alicante, Spain.
Ruth MoralesMolecular Laboratory, Instituto Bernabeu Biotech, 03016 Alicante, Spain.
Joaquín LlácerInstituto Bernabeu Reproductive Medicine, 03016 Alicante, Spain.
Jorge TenInstituto Bernabeu Reproductive Medicine, 03016 Alicante, Spain.
Juan Carlos CastilloInstituto Bernabeu Reproductive Medicine, 03016 Alicante, Spain.
Adoración RodríguezInstituto Bernabeu Reproductive Medicine, 03016 Alicante, Spain.
Rauf Nouni-GarcíaClinical Medicine Department, School of Medicine, University Miguel Hernández de Elche, 03550 Alicante, Spain.
Adriana López-PinedaClinical Medicine Department, School of Medicine, University Miguel Hernández de Elche, 03550 Alicante, Spain.ORCID 0000-0002-2117-0178
Belén MolinerInstituto Bernabeu Reproductive Medicine, 03016 Alicante, Spain.ORCID 0000-0003-0037-2747
Rafael BernabeuInstituto Bernabeu Reproductive Medicine, 03016 Alicante, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uterine microbiota may be involved in reproductive health and disease. This study aims to describe and compare the vaginal and endometrial microbiome patterns between women who became pregnant and women who did not after in vitro fertilization. We also compared the vaginal and endometrial microbiome patterns between women with and without a history of repeated implantation failures (RIF). This pilot prospective cohort study included 48 women presenting to the fertility clinic for IVF from May 2017 to May 2019. Women who achieved clinical pregnancy presented a greater relative abundance of

Indexed as

microbiomepregnancy ratesrepeated implantation failurereproductive medicine

Identifiers

PMID34575174
PMCPMC8465380

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.