Evidence map›Paper›PMID 34575166›Full record

ReviewJournal of clinical medicine2021

The Role of Fecal Microbiota Transplantation in the Treatment of Inflammatory Bowel Disease.

Magdalena Stojek, Anna Jabłońska, Krystian Adrych

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Magdalena StojekDepartment of Gastroenterology and Hepatology, Medical University of Gdansk, ul. Smoluchowskiego 17, 80-210 Gdańsk, Poland.ORCID 0000-0002-8167-8571
Anna JabłońskaDepartment of Gastroenterology and Hepatology, Medical University of Gdansk, ul. Smoluchowskiego 17, 80-210 Gdańsk, Poland.
Krystian AdrychDepartment of Gastroenterology and Hepatology, Medical University of Gdansk, ul. Smoluchowskiego 17, 80-210 Gdańsk, Poland.ORCID 0000-0001-6476-9095

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The exact pathogenesis of inflammatory bowel disease (IBD) is still not completely understood. It is hypothesized that a genetic predisposition leads to an exaggerated immune response to an environmental trigger, leading to uncontrolled inflammation. As there is no known causative treatment, current management strategies for inflammatory bowel disease focus on correcting the excessive immune response to environmental (including microbial) triggers. In recent years, there has been growing interest in new avenues of treatment, including targeting the microbial environment itself. Fecal microbiota transplantation (FMT) is a novel treatment modality showing promising results in early studies. The article discusses the rationale for the use of FMT in inflammatory bowel disease and the yet-unresolved questions surrounding its optimal use in practice.

Indexed as

Crohn’s diseasefecal microbiota transplantationinflammatory bowel diseaseulcerative colitis

Identifiers

PMID34575166
PMCPMC8465860

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.