ArticleJournal of clinical medicine2021
Clinical and Cytokine Profile in Patients with Early and Late Onset Meniere Disease.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 36 citations in OpenAlex.
- STING signaling in vestibular macrophages underlies Ménière's disease pathogenesis.Journal of neuroinflammation · 2026Article
- A Stress-Neuroendocrine-Myeloid Inflammation Axis Is Associated with the Progression of Ménière's Disease.Brain, behavior, & immunity - health · 2026Article
- Detecting endolymphatic hydrops in patients with cranial nerve VIII schwannoma using hydrops MR examination.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- A modern conceptual framework for study and treatment of Meniere's disease.Frontiers in neurology · 2025Review
- Distinctive clinical features of early and late-onset Ménière's disease.Frontiers in neurology · 2025Article
- Correlation of endolymphatic hydrops and perilymphatic enhancement with the clinical features of Ménière's disease.European radiology · 2024Article
- Cytokine profiling and transcriptomics in mononuclear cells define immune variants in Meniere Disease.Genes and immunity · 2024Article
- Exploring causal correlations between inflammatory cytokines and Ménière's disease: a Mendelian randomization.Frontiers in immunology · 2024Article
- Article
- A study of efficacy of Nigella sativa in treatment of Meniere's disease: A randomized, placebo controlled clinical trial.Journal of otology · 2023Article
- Vestibular migraine or Meniere's disease: a diagnostic dilemma.Journal of neurology · 2023Review
- Recent advances in understanding molecular bases of Ménière's disease.Faculty reviews · 2023Review
- Population-based study for the comorbidities and associated factors in Ménière's disease.Scientific reports · 2022Article
- NaCl exposure results in increased expression and processing of IL-1β in Meniere's disease patients.Scientific reports · 2022Article
- Role of Inner Ear Macrophages and Autoimmune/Autoinflammatory Mechanisms in the Pathophysiology of Inner Ear Disease.Frontiers in neurology · 2022Review
Corrections and comments
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Authors and funding
12 authors at 8 institutions in 1 country.
Funding
Abstract
backgroundMeniere disease (MD) is an inner ear disorder associated with comorbidities such as autoimmune diseases or migraine. This study describes clinical and cytokine profiles in MD according to the age of onset of the condition.
methodsA cross-sectional study including 83 MD patients: 44 with early-onset MD (EOMD, <35 years old), and 39 with late-onset MD (LOMD, >50 years old), 64 patients with migraine and 55 controls was carried out. Clinical variables and cytokines levels of CCL3, CCL4, CCL18, CCL22, CXCL,1 and IL-1β were compared among the different groups.
resultsCCL18 levels were higher in patients with migraine or MD than in controls. Elevated levels of IL-1β were observed in 11.4% EOMD and in 10.3% LOMD patients and these levels were not dependent on the age of individuals. EOMD had a longer duration of the disease (
conclusionsPatients with EOMD have a higher prevalence of migraine than LOMD, but migraine is not associated with any cytokine profile in patients with MD. The levels of CCL18, CCL3, and CXCL4 were different between patients with MD or migraine and controls.
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