Evidence map›Paper›PMID 34575153›Full record

ArticleJournal of clinical medicine2021

N-Terminal Pro-Brain Natriuretic Peptide Plasma Levels Are Associated with Intermediate-Term Follow-Up Cancer in Coronary Patients.

José Tuñón, Ana Pello, Álvaro Aceña, Sergio Ramos-Cillán, Juan Martínez-Milla, Óscar González-Lorenzo, Jesús Fuentes-Antras, Nieves Tarín, Carmen Cristóbal, Luis M Blanco-Colio and 9 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 9 institutions in 1 country.

José TuñónDepartment of Cardiology, IIS-Fundación Jiménez Díaz, 28040 Madrid, Spain.ORCID 0000-0002-1373-0999
Ana PelloDepartment of Cardiology, IIS-Fundación Jiménez Díaz, 28040 Madrid, Spain.
Álvaro AceñaDepartment of Cardiology, IIS-Fundación Jiménez Díaz, 28040 Madrid, Spain.
Sergio Ramos-CillánDepartment of Medicine, School of Medicine, Autónoma University, 28040 Madrid, Spain.
Juan Martínez-MillaDepartment of Cardiology, IIS-Fundación Jiménez Díaz, 28040 Madrid, Spain.
Óscar González-LorenzoDepartment of Cardiology, IIS-Fundación Jiménez Díaz, 28040 Madrid, Spain.ORCID 0000-0003-4342-8050
Jesús Fuentes-AntrasDepartment of Oncology, Hospital Clínico Universitario San Carlos, 28040 Madrid, Spain.
Nieves TarínDepartment of Cardiology, Hospital Universitario de Móstoles, 28040 Madrid, Spain.
Carmen CristóbalDepartment of Cardiology, Hospital de Fuenlabrada, 28040 Madrid, Spain.
Luis M Blanco-ColioLaboratory of Vascular Pathology, IIS-Fundación Jiménez Díaz, 28040 Madrid, Spain.ORCID 0000-0002-1560-6609
José Luis Martín-VenturaDepartment of Medicine, School of Medicine, Autónoma University, 28040 Madrid, Spain.
Ana HuelmosDepartment of Cardiology, Hospital Universitario Fundación Alcorcón, 28040 Madrid, Spain.
Carlos Gutiérrez-LandaluceDepartment of Cardiology, Hospital de Fuenlabrada, 28040 Madrid, Spain.ORCID 0000-0001-5807-0894
Marta López-CastilloDepartment of Cardiology, IIS-Fundación Jiménez Díaz, 28040 Madrid, Spain.
Joaquín AlonsoDepartment of Medicine, School of Medicine, Rey Juan Carlos University, Alcorcón, 28040 Madrid, Spain.
Lorenzo López BescósDepartment of Medicine, School of Medicine, Rey Juan Carlos University, Alcorcón, 28040 Madrid, Spain.
Jesús EgidoDepartment of Medicine, School of Medicine, Autónoma University, 28040 Madrid, Spain.
Ignacio Mahíllo-FernándezResearch Unit, IIS-Fundación Jiménez Díaz, 28040 Madrid, Spain.ORCID 0000-0003-0558-6541
Óscar LorenzoDepartment of Medicine, School of Medicine, Autónoma University, 28040 Madrid, Spain.ORCID 0000-0001-5515-6078
Hospital Universitario Fundación Jiménez Díaz · ESCentro de Investigación en Red en Enfermedades Cardiovasculares · ESUniversidad Rey Juan Carlos · ESCentro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas · ESHospital Clínico San Carlos · ESHospital Universitario de Fuenlabrada · ESHospital Universitario de Móstoles · ESHospital Universitario Fundación Alcorcón · ESUniversidad Autónoma de Madrid · ES

Funding

Fondo de Investigaciones Sanitarias PI05/0451, PI14/1567, PI17/01615, P20/00923Instituto de Salud Carlos III FEDER RD09/0076/00101Ministerio de Ciencia e Innovación RTC2019-006826-1RECAVA RD06/0014/0035Spanish Society of Atherosclerosis No reference number
6 · The paper itself

Abstract

N-terminal pro-brain natriuretic peptide (NT-proBNP) plasma levels are increased in patients with cancer. In this paper, we test whether NT-proBNP may identify patients who are going to receive a future cancer diagnosis (CD) in the intermediate-term follow-up. We studied 962 patients with stable coronary artery disease and free of cancer and heart failure at baseline. This sample represents a re-analysis of a previous work expanding the sample size and the follow-up. NT-proBNP, galectin-3, monocyte chemoattractant protein-1, high-sensitivity C-reactive protein, high-sensitivity cardiac troponin I (hsTnI), and calcidiol (vitamin D) plasma levels were assessed. The primary outcome was new CD. After 5.40 (2.81-6.94) years of follow-up, 59 patients received a CD. NT-proBNP [HR 1.036 CI (1.015-1.056) per increase in 100 pg/mL;

Indexed as

biomarkercancercoronary artery diseaseN-terminal pro-brain natriuretic peptidetumor

Identifiers

PMID34575153
PMCPMC8466930
OpenAlexW3198058746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.