Evidence map›Paper›PMID 34575031›Full record

ArticleLife (Basel, Switzerland)2021

The Association between 5-Hydroxytryptamine Receptor 1B rs13212041 Polymorphism and Trait Anxiety in Chinese Han College Subjects.

Xiaofei Ruan, Suwen Fang, Qi Zheng, Senqing Qi, Yingfang Tian, Wei Ren

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiaofei RuanKey Laboratory of Modern Teaching Technology, Ministry of Education, Xi'an 710062, China.
Suwen FangCollege of Life Sciences, Shaanxi Normal University, Xi'an 710119, China.
Qi ZhengCollege of Life Sciences, Shaanxi Normal University, Xi'an 710119, China.
Senqing QiCollege of Life Sciences, Shaanxi Normal University, Xi'an 710119, China.
Yingfang TianKey Laboratory of Modern Teaching Technology, Ministry of Education, Xi'an 710062, China.
Wei RenKey Laboratory of Modern Teaching Technology, Ministry of Education, Xi'an 710062, China.
Ministry of Education of the People's Republic of China · CNShaanxi Normal University · CN

Funding

Fundamental Research Funds for the Central Universities GK202005001Fundamental Research Funds for the Central Universities GK202105001National Natural Science Foundation of China 81971285Natural Science Foundation of Shaanxi Province 2020JM-306
6 · The paper itself

Abstract

Trait anxiety is a vulnerable personality factor for anxiety and depression. High levels of trait anxiety confer an elevated risk for the development of anxiety and other psychiatric disorders. There is evidence that 5-hydroxytryptamine receptor 1B (5-HT1B) gene polymorphisms play an important role in emotional disorders. Genotyping for four single-nucleotide polymorphisms (SNP) (rs11568817, rs130058, rs6297, and rs13212041) was conducted for 388 high trait anxious (HTA) individuals and 463 low traitanxious (LTA) individuals in Chinese Han college subjects. The results showed that the frequencies of the C-allele and TC + CC genotype of rs13212041 in the LTA individuals were higher than that in the HTA individuals (

Indexed as

5-hydroxytryptamine receptor 1B (5-HT1B)associationgene polymorphismssingle-nucleotide polymorphisms (SNP)trait anxiety

Identifiers

PMID34575031
PMCPMC8468159
OpenAlexW3197794391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.