Evidence map›Paper›PMID 34575030›Full record

ArticleLife (Basel, Switzerland)2021

Low Levels of Serum Fetuin-A and Retinol-Binding Protein 4 Correlate with Lipoprotein Subfractions in Morbid Obese and Lean Non-Diabetic Subjects.

Hajnalka Lőrincz, Imre Csige, Mariann Harangi, Anita Szentpéteri, Ildikó Seres, Zoltán Szabó, György Paragh, Sándor Somodi

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hajnalka LőrinczDepartment of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Imre CsigeDepartment of Emergency Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Mariann HarangiDepartment of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Anita SzentpéteriDepartment of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Ildikó SeresDepartment of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Zoltán SzabóDepartment of Emergency Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
György ParaghDepartment of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Sándor SomodiDepartment of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
University of Debrecen · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFetuin-A and retinol-binding protein 4 (RBP4) are secreted as both hepatokine and adipokine. These are involved in insulin resistance, obesity-related dyslipidemia, and atherosclerosis. To date, correlations of circulating fetuin-A and RBP4 with lipoprotein subfractions as well as high-density lipoprotein (HDL)-linked proteins have not been entirely investigated in morbid obese and lean non-diabetic subjects.

methodsOne-hundred obese non-diabetic patients (body mass index, BMI: 42.5 ± 8.1 kg/m

resultsSerum fetuin-A and RBP4 were unexpectedly lower in obese patients (

conclusionsOur data may indicate a potential role of fetuin-A and RBP4 in impaired lipoprotein metabolism associated with obesity.

Indexed as

diabetesfetuin-Ainsulin resistancelipoproteinobesityretinol-binding protein 4

Identifiers

PMID34575030
PMCPMC8471801
OpenAlexW3196894937

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.