Evidence map›Paper›PMID 34575027›Full record

ArticleLife (Basel, Switzerland)2021

Accelerated Wound Healing Using a Novel Far-Infrared Ceramic Blanket.

Frederick Robert Carrick, Luis Sebastian Alexis Valerio, Maxine N Gonzalez-Vega, David Engel, Kiminobu Sugaya

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Frederick Robert CarrickCollege of Medicine, University of Central Florida, Orlando, FL 32816, USA.ORCID 0000-0002-2818-6551
Luis Sebastian Alexis ValerioBurnett School of Biomedical Science, University of Central Florida, Orlando, FL 32816, USA.ORCID 0000-0001-8972-1223
Maxine N Gonzalez-VegaBurnett School of Biomedical Science, University of Central Florida, Orlando, FL 32816, USA.ORCID 0000-0003-0410-1565
David EngelBurnett School of Biomedical Science, University of Central Florida, Orlando, FL 32816, USA.
Kiminobu SugayaCollege of Medicine, University of Central Florida, Orlando, FL 32816, USA.ORCID 0000-0002-2788-5457

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWounds are associated with ranges of simple to complex disruption or damage to anatomical structure and function. They are also associated with enormous economic and social costs, increasing yearly, resulting in a severe impact on the wellbeing of individuals and society. Technology that might accelerate wound healing is associated with many benefits to injured people.

methodsBALBc mice underwent symmetrical excisional wounds through the panniculus carnosus. They were divided into a treatment group placed on an autonomous ceramic far-field infrared blanket (cIFRB) and a control group maintained under standard conditions. We also expanded and cultured adipose tissue-derived mesenchymal stem cells (MSCs) on cIFRB and compared them to standard conditions subjected to a scratch injury to compare survival, proliferation, and wound healing.

resultsThe wound healing of the cIRFB treatment group was significantly faster than the control group of mice. The wound-healing effect of mesenchymal stem cells on cIRFB was also increased and associated with significant migration to the wound area.

conclusionsWound healing is improved in a mouse model exposed to cFIRB. The ceramic blanket also promotes survival, proliferation, increased migration, and wound healing of MSCs without affecting their survival and proliferation. The utilization of cFIRB in cellular biology and medical applications may be promising in many situations currently explored in animal and human models. This technology needs no direct or battery power source and is entirely autonomous and noninvasive, making its application possible in any environment.

Indexed as

ceramicfar field infraredmesenchymal stem cellsmouse modelregenerationwound healing

Identifiers

PMID34575027
PMCPMC8469926

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.