Evidence map›Paper›PMID 34574886›Full record

ArticleHealthcare (Basel, Switzerland)2021

Clinical Findings among Patients with Respiratory Symptoms Related to Moisture Damage Exposure at the Workplace-The SAMDAW Study.

Pia Nynäs, Sarkku Vilpas, Elina Kankare, Jussi Karjalainen, Lauri Lehtimäki, Jura Numminen, Antti Tikkakoski, Leenamaija Kleemola, Jukka Uitti

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Pia NynäsFaculty of Medicine and Health Technology, Tampere University, 33520 Tampere, Finland.ORCID 0000-0002-0704-8862
Sarkku VilpasDepartment of Phoniatrics, Tampere University Hospital, 33520 Tampere, Finland.ORCID 0000-0002-2006-1682
Elina KankareDepartment of Phoniatrics, Tampere University Hospital, 33520 Tampere, Finland.
Jussi KarjalainenAllergy Centre, Tampere University Hospital, 33520 Tampere, Finland.
Lauri LehtimäkiFaculty of Medicine and Health Technology, Tampere University, 33520 Tampere, Finland.
Jura NumminenAllergy Centre, Tampere University Hospital, 33520 Tampere, Finland.ORCID 0000-0003-4211-4244
Antti TikkakoskiDepartment of Clinical Physiology and Nuclear Medicine, Tampere University Hospital, 33520 Tampere, Finland.
Leenamaija KleemolaFaculty of Medicine and Health Technology, Tampere University, 33520 Tampere, Finland.
Jukka UittiFaculty of Medicine and Health Technology, Tampere University, 33520 Tampere, Finland.
Tampere University Hospital · FITampere University · FI

Funding

Hengityssairauksien Tutkimussäätiö N.A.Orionin Tutkimussäätiö N.A.Suomen Lääketieteen Säätiö N.A.Tampereen Tuberkuloosisäätiö N.A.the Competitive State Research Financing of the Expert Responsibility Area of Tampere University Hospital 9T069The Finnish ORL-HNS Foundation N.A.
6 · The paper itself

Abstract

backgroundRespiratory tract symptoms are associated with workplace moisture damage (MD). The focus of this observational clinical study was patients with workplace MD-associated symptoms, to evaluate the usefulness of different clinical tests in diagnostics in secondary healthcare with a special interest in improving the differential diagnostics between asthma and laryngeal dysfunction.

methodsIn patients referred because of workplace MD-associated respiratory tract symptoms, we sought to systematically assess a wide variety of clinical findings.

resultsNew-onset asthma was diagnosed in 30% of the study patients. Laryngeal dysfunction was found in 28% and organic laryngeal changes in 22% of the patients, and these were common among patients both with and without asthma. Most of the patients (85%) reported a runny or stuffy nose, and 11% of them had chronic rhinosinusitis. Atopy was equally as common as in the general population.

conclusionsAs laryngeal changes were rather common, we recommend proper differential diagnostics with lung function testing and investigations of the larynx and its functioning, when necessary, in cases of prolonged workplace MD-associated symptoms. Chronic rhinosinusitis among these patients was not uncommon. Based on this study, allergy testing should not play a major role in the examination of these patients.

Indexed as

asthmadampnessirritable larynxlaryngeal dysfunctionmoisture damagemoldrespiratory symptomsworkplace

Identifiers

PMID34574886
PMCPMC8466522
OpenAlexW3198696858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.