Evidence map›Paper›PMID 34574706›Full record

ReviewInternational journal of environmental research and public health2021

Interstitial Ectopic Pregnancy: The Role of Mifepristone in the Medical Treatment.

Guglielmo Stabile, Federico Romano, Giulia Zinicola, Ghergana Alexandrova Topouzova, Giovanni Di Lorenzo, Francesco Paolo Mangino, Giuseppe Ricci

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
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  8. Article
  9. Endometrial Changes Associated with Mifepristone: A Review.International journal of general medicine · 2025
    Review
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Guglielmo StabileInstitute for Maternal and Child Health IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0001-9266-3896
Federico RomanoInstitute for Maternal and Child Health IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0003-2157-8330
Giulia ZinicolaDepartment of Medicine, Surgery and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Ghergana Alexandrova TopouzovaDepartment of Medicine, Surgery and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Giovanni Di LorenzoInstitute for Maternal and Child Health IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0002-8845-1206
Francesco Paolo ManginoInstitute for Maternal and Child Health IRCCS "Burlo Garofolo", 34137 Trieste, Italy.
Giuseppe RicciInstitute for Maternal and Child Health IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0002-8031-1102
IRCCS Materno Infantile Burlo Garofolo · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interstitial pregnancy is defined as the presence of a gestational sac in the most proximal section of the fallopian tube. Management of interstitial pregnancy remains a debated topic. Depending on hemodynamic stability, size of pregnancy, depth of surrounding myometrium, and desires for future fertility, interstitial pregnancy can be managed medically or surgically. We reviewed the literature in December 2020 using keywords "interstitial pregnancy", "medical treatment", "methotrexate", and "mifepristone". Articles published from January 1991 until 2020 were obtained from databases EMBASE, SCOPUS, and PUBMED. We describe the case of a patient with an interstitial pregnancy that was managed with a total medical approach in August 2020 at Burlo Garofolo Hospital. The patient was asymptomatic and hemodynamically stable, with a high level of serum

Indexed as

MifepristonePregnancy, InterstitialFemaleFertilityHumansMethotrexateMyometriumPregnancyMethotrexateMifepristoneconservative treatmentectopic pregnancyfertility sparinginterstitial pregnancymedical therapymethotrexatemifepristone

Identifiers

PMID34574706
PMCPMC8472240
OpenAlexW3200503760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.