Evidence map›Paper›PMID 34574676›Full record

Trial reportInternational journal of environmental research and public health2021

Oxidative Stress and Inflammation, MicroRNA, and Hemoglobin Variations after Administration of Oxygen at Different Pressures and Concentrations: A Randomized Trial.

Gerardo Bosco, Matteo Paganini, Tommaso Antonio Giacon, Alberto Oppio, Alessandra Vezzoli, Cinzia Dellanoce, Tatiana Moro, Antonio Paoli, Federica Zanotti, Barbara Zavan and 2 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Hyperbaric Oxygen Therapy in Experimental Autoimmune Myocarditis: Insights from Preclinical Models to Translational Perspectives.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  6. Review
  7. Oxy-inflammation in hyperbaric oxygen therapy applications.European journal of translational myology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Hyperoxia: Effective Mechanism of Hyperbaric Treatment at Mild-Pressure.International journal of molecular sciences · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Gerardo BoscoDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0001-6595-7944
Matteo PaganiniDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-7556-6928
Tommaso Antonio GiaconDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-1155-0628
Alberto OppioDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0001-9462-6079
Alessandra VezzoliInstitute of Clinical Physiology, National Research Council (CNR), 20162 Milan, Italy.
Cinzia DellanoceInstitute of Clinical Physiology, National Research Council (CNR), 20162 Milan, Italy.
Tatiana MoroDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-1404-1511
Antonio PaoliDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0003-0474-4229
Federica ZanottiDepartment of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
Barbara ZavanDepartment of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
Costantino BalestraEnvironmental, Occupational, Ageing (Integrative) Physiology Laboratory, Haute Ecole Bruxelles-Brabant (HE2B), 1180 Brussels, Belgium.ORCID 0000-0001-6771-839X
Simona Mrakic-SpostaInstitute of Clinical Physiology, National Research Council (CNR), 20162 Milan, Italy.ORCID 0000-0001-7359-2690
University of Padua · ITNational Research Council · ITUniversity of Ferrara · ITHaute École de Bruxelles · BE

Funding

Crocicchia Srl private fundsZamperla spa private funds
6 · The paper itself

Abstract

Exercise generates reactive oxygen species (ROS), creating a redox imbalance towards oxidation when inadequately intense. Normobaric and hyperbaric oxygen (HBO) breathed while not exercising induces antioxidant enzymes expression, but literature is still poor. Twenty-two athletes were assigned to five groups: controls; 30%, or 50% O

Indexed as

Hyperbaric OxygenationMicroRNAsHumansInflammationOxidative StressOxygenMicroRNAsOxygenhyperbaric oxygen therapyhyperoxiaoxygenredox state

Identifiers

PMID34574676
PMCPMC8468581
OpenAlexW3199676117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.