Evidence map›Paper›PMID 34574472›Full record

ArticleInternational journal of environmental research and public health2021

The Disappearance of Respiratory Viruses in Children during the COVID-19 Pandemic.

Anna Chiara Vittucci, Livia Piccioni, Luana Coltella, Claudia Ciarlitto, Livia Antilici, Elena Bozzola, Fabio Midulla, Paolo Palma, Carlo Federico Perno, Alberto Villani

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 4 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 4 syntheses or guidelines pooled it, 93 citations in OpenAlex.

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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Anna Chiara VittucciGeneral Pediatrics Unit, Pediatric Emergency and General Pediatrics Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Livia PiccioniUnit of Microbiology and Diagnostic Immunology, Department of Diagnostic and Laboratory Medicine, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Luana ColtellaUnit of Microbiology and Diagnostic Immunology, Department of Diagnostic and Laboratory Medicine, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Claudia CiarlittoGeneral Pediatrics Unit, Pediatric Emergency and General Pediatrics Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Livia AntiliciGeneral Pediatrics Unit, Pediatric Emergency and General Pediatrics Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Elena BozzolaGeneral Pediatrics Unit, Pediatric Emergency and General Pediatrics Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0001-5947-2414
Fabio MidullaDepartment of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Paolo PalmaClinical Immunology and Vaccinology Unit, Academic Department of Pediatrics, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Carlo Federico PernoUnit of Microbiology and Diagnostic Immunology, Department of Diagnostic and Laboratory Medicine, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Alberto VillaniGeneral Pediatrics Unit, Pediatric Emergency and General Pediatrics Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0002-9120-0424
Bambino Gesù Children's Hospital · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSocial distancing measures are used to reduce the spreading of COVID-19. The aim of this study was to assess the impact of local restrictions on the transmission of respiratory virus infections.

methodswe retrospectively analyzed the nasopharyngeal samples of all patients (0-18 years old) admitted with respiratory symptoms in a large Italian tertiary hospital during the last three seasons from 2018 to 2021.

resultsA strong reduction in all viral respiratory infections was observed in the last season (2020-2021) compared to the two previous seasons (-79.69% and -80.66%, respectively). In particular, we found that during the epidemic period 2018-2019 and 2019-2020, the total number of Respiratory Syncytial Virus (RSV) cases was, respectively 726 and 689, while in the last season a total of five cases was detected. In the first months of 2018-2019 and 2019-2020, the total flu infections were 240 and 354, respectively, while in the last season we did not detect any influenza virus. As other viruses, the presence of Rhinovirus declined, but to a lesser extent: a total of 488 cases were assessed compared to the 1030 and 1165 cases of the two previous respective epidemic seasons.

conclusionsPublic health interventions and distancing (including continuous use of face masks) settled to counter the pandemic spread of COVID-19 had a macroscopic impact on all respiratory virus transmission and related diseases, with a partial exception of Rhinovirus. The absence of viruses' circulation could result in a lack of immunity and increased susceptibility to serious infections in the next seasons.

Indexed as

COVID-19Influenza, HumanRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsVirusesAdolescentChildChild, PreschoolHumansInfantInfant, NewbornPandemicsRetrospective StudiesSARS-CoV-2SeasonschildhoodCOVID-19pandemicrespiratory virusessocial distancingviral infections

Identifiers

PMID34574472
PMCPMC8467075
OpenAlexW3200527716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.