ReviewDiagnostics (Basel, Switzerland)2021
Patient-Reported Outcomes and Preferences for Colon Capsule Endoscopy and Colonoscopy: A Systematic Review with Meta-Analysis.
Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06475560 (Camera Capsule Endoscopy in the Routine Diagnostic Pathway for Colorectal Diseases), which is not on this map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Camera Capsule Endoscopy in the Routine Diagnostic Pathway for Colorectal Diseases
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Follow-up endoscopy rates as an indicator of effectiveness in colon capsule endoscopy: a systematic review and meta-analysis.BMJ open gastroenterology · 2025Pooled it
- Acceptability of alternative technologies compared with faecal immunochemical test and/or colonoscopy in colorectal cancer screening: A systematic review.Journal of medical screening · 2023Pooled it
- Trial
- Trial
- Colon Capsule Endoscopy in the Routine Diagnostic Pathway for Colorectal Diseases (DanCap): Protocol for a Cluster-Allocated Crossover Trial.Diagnostics (Basel, Switzerland) · 2026Article
- Defining post-colon capsule endoscopy colorectal cancer (pCCECRC)-an International Capsule Endoscopy Research (iCARE) group consensus statement.Surgical endoscopy · 2026Article
- Associations between patient characteristics and completeness of colon capsule endoscopy in colorectal cancer screening participants: a cross-sectional study.BMJ open gastroenterology · 2026Article
- Expected Values of Artificial Intelligence in Colon Capsule Endoscopy: Artificial Intelligence in Capsule Endoscopy Consortium Position Statement.Endoscopy international open · 2026Article
- Inter- and Intra-Observer Reliability for Colon Capsule CLEansing Assessment and Report.Endoscopy international open · 2026Article
- Prospective, Multicentre Feasibility Study of Remote Colon Capsule Endoscopy Using the OMOM CC100 System.Diagnostics (Basel, Switzerland) · 2025Article
- Beyond diagnostic test performance: two content-validated questionnaires assessing patient and clinician satisfaction with diagnostic tests.Journal of patient-reported outcomes · 2025Article
- Patient experience of colon capsule endoscopy in clinical practice: a structured, comparative patient survey.BMJ open gastroenterology · 2025Article
- Patient priorities and decision-making process when choosing between colonic investigation alternatives: a qualitative interview study.BMJ open gastroenterology · 2025Observational
- Colon capsule endoscopy is an effective filter test for colonic polyp surveillance.World journal of gastrointestinal endoscopy · 2025Article
- Introducing colon capsule endoscopy as a new diagnostic modality for patients with bowel symptoms in general practice: a feasibility study.BMC primary care · 2025Article
- Factors predicting conversion from colon capsule endoscopy to conventional optical endoscopy-findings from the CESCAIL study.BMC gastroenterology · 2025Article
- Multicentre Study of 10,369 Symptomatic Patients Comparing the Diagnostic Accuracy of Colon Capsule Endoscopy, Colonoscopy and CT Colonography.Alimentary pharmacology & therapeutics · 2025Article
- Conference Report: The FutuRE oF MinimalLy InvasivE GI and Capsule DiagnosTics (REFLECT) Nyborg, Denmark, October 2023.Diagnostics (Basel, Switzerland) · 2024Article
- Interobserver agreement on landmark and flexure identification in colon capsule endoscopy.Techniques in coloproctology · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 7 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colon capsule endoscopy as an alternative to colonoscopy for the diagnosis of colonic disease may serve as a less invasive and more tolerable investigation for patients. Our aim was to examine patient-reported outcomes for colon capsule endoscopy compared to conventional optical colonoscopy including preference of investigation modality, tolerability and adverse events. A systematic literature search was conducted in Web of Science, PubMed and Embase. Search results were thoroughly screened for in- and exclusion criteria. Included studies underwent assessment of transparency and completeness, after which, data for meta-analysis were extracted. Pooled estimates of patient preference were calculated and heterogeneity was examined including univariate meta-regressions. Patient-reported tolerability and adverse events were reviewed. Out of fourteen included studies, twelve had investigated patient-reported outcomes in patients who had undergone both investigations, whereas in two the patients were randomized between investigations. Pooled patient preferences were estimated to be 52% (CI 95%: 41-63%) for colon capsule endoscopy and 45% (CI 95%: 33-57%) for conventional colonoscopy: not indicating a significant difference. Procedural adverse events were rarely reported by patients for either investigation. The tolerability was high for both colon capsule endoscopy and conventional colonoscopy. Patient preferences for conventional colonoscopy and colon capsule endoscopy were not significantly different. Procedural adverse events were rare and the tolerability for colon capsule endoscopy was consistently reported higher or equal to that of conventional colonoscopy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.