Evidence map›Paper›PMID 34574032›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Intraoperative Lung Ultrasound (ILU) for the Assessment of Pulmonary Nodules.

Marco Taurchini, Carla Maria Irene Quarato, Elisabetta Maria Frongillo, Gian Maria Ferretti, Cristiana Cipriani, Marco Bizzarri, Maria Pia Foschino Barbaro, Donato Lacedonia, Annalisa Simeone, Paolo Graziano and 5 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Intraoperative Contrast-Enhanced Ultrasound Versus Traditional Intraoperative Ultrasound for Detecting Lung Nodules During Robotic-assisted Thoracic Surgery.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. The Positioning Method of Pulmonary Nodules in Thoracoscopic Surgery Based on CT Simulation Positioning System for Radiotherapy.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. 'Now you can see me, now you don't': seeking the invisible lung nodule.Interdisciplinary cardiovascular and thoracic surgery · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Marco TaurchiniUnit of Thoracic Surgery, IRCCS Fondazione "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Carla Maria Irene QuaratoDepartment of Medical and Surgical Sciences, Institute of Respiratory Diseases, Policlinico Universitario "Riuniti" di Foggia, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0003-4299-7403
Elisabetta Maria FrongilloUnit of Thoracic Surgery, Cliniche Humanitas Gavazzeni, 24125 Bergamo, Italy.
Gian Maria FerrettiUnit of Thoracic Surgery, IRCCS Fondazione "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Cristiana CiprianiDepartment of Internal Medicine and Medical Disciplines, Sapienza University, 00161 Rome, Italy.ORCID 0000-0002-0141-1202
Marco BizzarriUnit of Thoracic Surgery, IRCCS Fondazione "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Maria Pia Foschino BarbaroDepartment of Medical and Surgical Sciences, Institute of Respiratory Diseases, Policlinico Universitario "Riuniti" di Foggia, University of Foggia, 71122 Foggia, Italy.
Donato LacedoniaDepartment of Medical and Surgical Sciences, Institute of Respiratory Diseases, Policlinico Universitario "Riuniti" di Foggia, University of Foggia, 71122 Foggia, Italy.
Annalisa SimeoneUnit of Radiology, IRCCS Fondazione "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Paolo GrazianoUnit of Pathology, IRCCS Fondazione "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.ORCID 0000-0001-7066-7896
Lucia DimitriUnit of Pathology, IRCCS Fondazione "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Evaristo MaielloUnit of Oncology, IRCCS Fondazione "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.ORCID 0000-0003-3890-3435
Lucio CavaliereUnit of Reanimation and Anesthesiology, IRCCS Fondazione "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Salvatore De CosmoDepartment of Internal Medicine, IRCCS Fondazione "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.
Marco SperandeoUnit of Interventional and Diagnostic Ultrasound of Internal Medicine, IRCCS Fondazione "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Italy.ORCID 0000-0001-6685-6942

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe primary aim of this study was to confirm the validity of intraoperative lung ultrasound (ILU) as a safe and effective method of localization for difficult to visualize pulmonary nodules during Video-Assisted Thoracoscopic Surgery (VATS) and open thoracotomy. The secondary aim was to enhance knowledge on the morphological patterns of presentation of pulmonary nodules on direct ultrasound examination. MATERIALS AND

methods131 patients with lung nodule and indication for surgery were enrolled. All patients underwent pre-operative imaging of the chest, including Chest Computed Tomography (CT) and Transthoracic Ultrasound (TUS), and surgical procedures for histological assessment of pulmonary nodules (VATS or open thoracotomy).

resultsThe identification of 100.00% of lung nodules was allowed by ILU, while the detection rate of digital palpation was 94.66%. It was not possible to associate any specific ILU echostructural pattern to both benign or malignant lesions. However, the actual histological margins of the lesions in the operating samples were corresponding to those visualized at ILU in 125/131 (95.42%) cases. No complications have been reported with ILU employment.

conclusionsIn our experience, ILU performed during both open surgery and VATS demonstrated to be a reliable and safe method for visualization and localization of pulmonary nodules non previously assessed on digital palpation. In addition, ILU showed to allow a clear nodule's margins' definition matching, in most cases, with the actual histological margins.

Indexed as

intraoperative ultrasoundlung nodulesthoracic surgerytransthoracic ultrasoundultrasound

Identifiers

PMID34574032
PMCPMC8466360

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.