Evidence map›Paper›PMID 34574021›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Pediatric Extraspinal Sacrococcygeal Ependymoma: Report of Two Cases and Literature Review.

Francesco Fabozzi, Silvia Ceccanti, Antonella Cacchione, Giovanna Stefania Colafati, Andrea Carai, Alessandro Crocoli, Angela Mastronuzzi, Denis A Cozzi

Open access · goldAbstract readCase Reports
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Extraspinal sacrococcygeal anaplastic ependymoma: A case report.International journal of surgery case reports · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Francesco FabozziDepartment of Hematology/Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, 00165 Rome, Italy.
Silvia CeccantiPediatric Surgery Unit, Sapienza University of Rome, AOU Policlinico Umberto I, 00161 Rome, Italy.
Antonella CacchioneDepartment of Hematology/Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, 00165 Rome, Italy.ORCID 0000-0003-4901-9952
Giovanna Stefania ColafatiNeuroradiology Unit, Department of Imaging, IRCCS Bambino Gesù Children's Hospital, 00165 Rome, Italy.ORCID 0000-0002-1142-4904
Andrea CaraiNeurosurgery Unit, Department of Neurosciences, IRCCS Bambino Gesù Children's Hospital, 00165 Rome, Italy.ORCID 0000-0002-5203-7855
Alessandro CrocoliDepartment of Pediatric Surgery, IRCCS Bambino Gesù Children's Hospital, 00165 Rome, Italy.ORCID 0000-0003-2157-4233
Angela MastronuzziDepartment of Hematology/Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, 00165 Rome, Italy.ORCID 0000-0002-4408-2373
Denis A CozziPediatric Surgery Unit, Sapienza University of Rome, AOU Policlinico Umberto I, 00161 Rome, Italy.ORCID 0000-0002-7290-3837
Bambino Gesù Children's Hospital · ITPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary central nervous system (CNS) tumors represent the most common solid tumors in childhood. Ependymomas arise from ependymal cells lining the wall of ventricles or central canal of spinal cord and their occurrence outside the CNS is extremely rare, published in the literature as case reports or small case series. We present two cases of extra-CNS myxopapillary ependymomas treated at our institution in the past three years; both cases originate in the sacrococcygeal region and were initially misdiagnosed as epidermoid cyst and germ cell tumor, respectively. The first case, which arose in a 9-year-old girl, was treated with a surgical excision in two stages, due to the non-radical manner of the first operation; no recurrence was observed after two years of follow-up. The other case was a 12-year-old boy who was treated with a complete resection and showed no evidence of recurrence at one-year follow-up. In this paper, we report our experience in treating an extremely rare disease that lacks a standardized approach to diagnosis, treatment and follow-up; in addition, we perform a literature review of the past 35 years.

Indexed as

extra-CNS ependymomamyxopapillary ependymomapediatric ependymomapilonidal disease

Identifiers

PMID34574021
PMCPMC8471863
OpenAlexW3199408337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.