Evidence map›Paper›PMID 34573894›Full record

ReviewDiagnostics (Basel, Switzerland)2021

Atopic Dermatitis-Beyond the Skin.

Mădălina Mocanu, Dan Vâță, Anisia-Iuliana Alexa, Laura Trandafir, Adriana-Ionela Patrașcu, Mădălina Florina Hâncu, Laura Gheucă-Solovăstru

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Journal of microbiology and biotechnology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Gut microbes · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. The Acari Hypothesis, III: Atopic Dermatitis.Pathogens (Basel, Switzerland) · 2022
    Article
  20. A comprehensive summary of disease variants implicated in metal allergy.Journal of toxicology and environmental health. Part B, Critical reviews · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mădălina MocanuDepartment of Oral Dermatology, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Dan VâțăDepartment of Dermatology, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Anisia-Iuliana AlexaDepartment of Ophthalmology, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Laura TrandafirDepartment of Mother and Child Medicine-Pediatrics, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Adriana-Ionela PatrașcuDermatology Clinic, "St. Spiridon" County Emergency Clinical Hospital, 700111 Iași, Romania.
Mădălina Florina HâncuDermatology Clinic, "St. Spiridon" County Emergency Clinical Hospital, 700111 Iași, Romania.
Laura Gheucă-SolovăstruDepartment of Dermatology, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Grigore T. Popa University of Medicine and Pharmacy · ROSpitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis is a chronic inflammatory disease that can arise during the first months of life or at maturity and have a significant negative impact on the quality of life. The main pathogenic mechanism is the breakdown of cutaneous barrier integrity, which is associated with systemic inflammatory immunologic disorders. Atopic dermatitis involves numerous immunologic, allergic, respiratory, and ophthalmologic comorbidities that develop through similar intricate pathogenic phenomena. The atopic march represents the evolution in time of various allergic diseases, of which food allergies often cause the first manifestations of atopy, even from a very young age. Chronic inflammation translated through specific markers, next to increased immunoglobulin E (IgE) serum levels and heterogenous clinical manifestations, argue for the inclusion of atopic dermatitis in the systemic disease category.

Indexed as

atopic dermatitischronic inflammationcomorbiditiesextra-cutaneous manifestations

Identifiers

PMID34573894
PMCPMC8464732
OpenAlexW3198733964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.