Evidence map›Paper›PMID 34573883›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Optical Coherence Tomography Angiography in Type 1 Diabetes Mellitus. Report 4: Glycated Haemoglobin.

Carolina Bernal-Morales, Aníbal Alé-Chilet, Ruben Martín-Pinardel, Marina Barraso, Teresa Hernández, Cristian Oliva, Irene Vinagre, Emilio Ortega, Marc Figueras-Roca, Anna Sala-Puigdollers and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03422965 (Evaluation of Microvascular Changes in the Perifoveal Vascular Network Using Optical Coherence Tomography Angiography), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03422965 naunknown statusnot on this map

Evaluation of Microvascular Changes in the Perifoveal Vascular Network Using Optical Coherence Tomography Angiography (OCT-A) in Type I Diabetes Mellitus

TypeinterventionalSponsorHospital Clinic of BarcelonaRan2017 to 2021Enrolled600ConditionsRetinal Vascular, Retinal Disease, Retinal Ischemia, Retinal Ischaemia Due to Type 1 Diabetes MellitusArmsOptical Coherence Tomography Angiography, Blood test, Urine test
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Carolina Bernal-MoralesInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.ORCID 0000-0001-5469-3963
Aníbal Alé-ChiletInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.ORCID 0000-0001-9479-4355
Ruben Martín-PinardelAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain.
Marina BarrasoInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.
Teresa HernándezInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.
Cristian OlivaInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.
Irene VinagreAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain.
Emilio OrtegaAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain.ORCID 0000-0002-2217-8905
Marc Figueras-RocaInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.ORCID 0000-0002-0548-0539
Anna Sala-PuigdollersInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.
Marga GimenezAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain.
Enric EsmatjesAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain.
Alfredo AdánInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.
Javier Zarranz-VenturaInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.ORCID 0000-0003-2338-8143
Hospital Clínic de Barcelona · ESCentro de Investigación Biomédica en Red · ESConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ES

Funding

Fundació la Marató de TV3 201633.10Instituto de Salud Carlos III PI18/00518
6 · The paper itself

Abstract

The purpose of this study was to evaluate specifically the relationship between glycated haemoglobin (HbA1c) levels and retinal optical coherence tomography (OCT) and OCT angiography (OCTA) parameters in type 1 Diabetes Mellitus (DM). A total of 478 type 1 DM patients and 115 controls were included in a prospective OCTA trial (ClinicalTrials.gov NCT03422965). Subgroup analysis was performed for controls, no diabetic retinopathy (DM-no DR) and DR patients (DM-DR), and HbA1c levels. OCT and OCTA measurements were compared with HbA1c levels (current and previous 5 years). DM-no DR patients with HbA1c levels >7.5% showed lower VD than DM-DR and controls (20.16 vs. 20.22 vs. 20.71,

Indexed as

diabetic retinopathyfoveal avascular zoneglycated haemoglobinHbA1cmacular thicknessoculomicsoptical coherence tomographyoptical coherence tomography angiographyperfusion densityvessel density

Identifiers

PMID34573883
PMCPMC8472643
OpenAlexW3194396959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.