Evidence map›Paper›PMID 34573702›Full record

ArticleAnimals : an open access journal from MDPI2021

Influence of Different Regimes of Moderate Maternal Feed Restriction during Pregnancy of Primiparous Rabbit Does on Long-Term Metabolic Energy Homeostasis, Productive Performance and Welfare.

Carlota Fernández-Pacheco, Pilar Millán, María Rodríguez, Nora Formoso-Rafferty, Ana Sánchez-Rodríguez, Pedro L Lorenzo, María Arias-Álvarez, Rosa M García-García, Pilar G Rebollar

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Carlota Fernández-PachecoDepartment of Physiology, Faculty of Veterinary, Complutense University of Madrid, Avenida Puerta de Hierro s/n, 28040 Madrid, Spain.ORCID 0000-0002-9226-1579
Pilar MillánDepartment of Physiology, Faculty of Veterinary, Complutense University of Madrid, Avenida Puerta de Hierro s/n, 28040 Madrid, Spain.ORCID 0000-0001-8932-8851
María RodríguezDepartment of Agrarian Production, ETSIAAB, Technical University of Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain.
Nora Formoso-RaffertyDepartment of Agrarian Production, ETSIAAB, Technical University of Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain.ORCID 0000-0003-2319-3485
Ana Sánchez-RodríguezDepartment of Physiology, Faculty of Veterinary, Complutense University of Madrid, Avenida Puerta de Hierro s/n, 28040 Madrid, Spain.ORCID 0000-0002-3724-9470
Pedro L LorenzoDepartment of Physiology, Faculty of Veterinary, Complutense University of Madrid, Avenida Puerta de Hierro s/n, 28040 Madrid, Spain.
María Arias-ÁlvarezDepartment of Animal Production, Faculty of Veterinary, Complutense University of Madrid, Avenida Puerta de Hierro s/n, 28040 Madrid, Spain.ORCID 0000-0001-7907-7454
Rosa M García-GarcíaDepartment of Physiology, Faculty of Veterinary, Complutense University of Madrid, Avenida Puerta de Hierro s/n, 28040 Madrid, Spain.ORCID 0000-0002-3393-8906
Pilar G RebollarDepartment of Agrarian Production, ETSIAAB, Technical University of Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain.ORCID 0000-0003-4418-0157
Universidad Complutense de Madrid · ESUniversidad Politécnica de Madrid · ES

Funding

Spanish Ministery of Economy and Competitiveness AGL2015-65572-C2-1-R and RTI2018-094404-B-C21
6 · The paper itself

Abstract

In this study, a maternal feed restriction (MFR; 105 g/d) in primiparous rabbit does was applied from day 0 to 7 post artificial insemination (AI) (R07, n = 96), from day 7 to 21 post AI (R721, n = 92), from day 0 to 21 post AI (R021, n = 94) or fed ad libitum during whole pregnancy (Control, n= 92). Feed intake (FI) was measured after MFR was over. On day 28 of gestation, fetoplacental development was evaluated (n = 11/group) and the productive parameters of the remaining dams were analyzed. Plasma free tri-iodothyronine (T3) and thyroxine, glucose, insulin, non-esterified fatty acids (NEFA), and corticosterone were analyzed during gestation and lactation (n = 5/group). After MFR, all groups significantly increased their voluntary FI. The longer MFR was, the lower the weight and length of the fetuses, but no long-term effects over litter performance were observed. R021 groups had the lowest T3 and the highest NEFA concentrations during pregnancy and showed insulin resistance at the end of gestation, but during lactation, energy homeostasis was balanced in all groups. MFR did not affect corticosterone concentrations. In conclusion, the ration setting applied slightly involved the energy homeostasis and metabolism of the animals, but their overall metabolic condition, productive performance and welfare were not compromised.

Indexed as

corticosteronefeed intakefetusfree tri-iodothyronineglucoseinsulinNEFAplacentarabbitthyroxine

Identifiers

PMID34573702
PMCPMC8470312
OpenAlexW3200848344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.