ArticleAnimals : an open access journal from MDPI2021
Early Life Fecal Microbiota Transplantation in Neonatal Dairy Calves Promotes Growth Performance and Alleviates Inflammation and Oxidative Stress during Weaning.
Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Pooled it
- Microbiome Engineering in Dairy Cattle: A Critical Review of Strategies for Disease Resistance, Productivity, and Sustainable Farming.Veterinary sciences · 2026Review
- Harnessing the early-life gut microbiome for sustainable ruminant production.Animal microbiome · 2026Review
- Effects of gut barrier dysfunction during a viral respiratory disease challenge on immune function of feedlot beef calves.Journal of animal science · 2026Article
- Dietary Oligosaccharides Alter Blood and Fecal Metabolites in Holstein Dairy Calves.Animals : an open access journal from MDPI · 2025Article
- Mechanisms and Applications of Gastrointestinal Microbiota-Metabolite Interactions in Ruminants: A Review.Microorganisms · 2025Review
- Mechanism and application of yeast and its culture in regulating intestinal antioxidant defense in ruminants.Frontiers in veterinary science · 2025Review
- Duration of dam contact had a long effect on calf rumen microbiota without affecting growth.Frontiers in veterinary science · 2025Article
- Freeze-dried fecal microorganisms as an effective biomaterial for the treatment of calves suffering from diarrhea.Scientific reports · 2024Article
- Article
- Effects of fecal microbiota transplantation on metabolic health of DBA mice.Frontiers in microbiology · 2024Article
- Fecal microbiota colonization dynamics in dairy heifers associated with early-life rumen microbiota modulation and gut health.Frontiers in microbiology · 2024Article
- Colonization of the Gastrointestinal Tract of Chicks with Different Bacterial Microbiota Profiles.Animals : an open access journal from MDPI · 2023Article
- Physiological Conditions Leading to Maternal Subclinical Ketosis in Holstein Dairy Cows Can Impair the Offspring's Postnatal Growth and Gut Microbiome Development.Microorganisms · 2023Article
- Microbial Interventions to Improve Neonatal Gut Health.Microorganisms · 2023Review
- Colonization and development of the gut microbiome in calves.Journal of animal science and biotechnology · 2023Review
- The Influence of Feeding with Colostrum and Colostrum Replacer on Major Blood Biomarkers and Growth Performance in Dairy Calves.Veterinary sciences · 2023Article
- Yeast Culture Supplementation Effects on Systemic and Polymorphonuclear Leukocytes' mRNA Biomarkers of Inflammation and Liver Function in Peripartal Dairy Cows.Animals : an open access journal from MDPI · 2023Article
- Modulating gastrointestinal microbiota to alleviate diarrhea in calves.Frontiers in microbiology · 2023Review
- Immunometabolism in livestock: triggers and physiological role of transcription regulators, nutrients, and microbiota.Animal frontiers : the review magazine of animal agriculture · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
This study aimed to evaluate the effects of early life fecal microbiota transplantation (FMT) on the health and performance of neonatal dairy calves. The donor was selected based on health and production records and fecal material testing negative for infectious pathogens. Sixteen healthy newborn Holstein calves were randomized to either a baseline nutritional program (CON) or 1×/d inoculations with 25 g of fecal donor material (FMT) mixed in the milk replacer (n = 8/TRT) from 8 to 12 days of age. Blood and fecal samples were collected weekly, and calves were weaned at 7 weeks of age. A TRT × Week interaction was observed in haptoglobin, which was reflected in a positive quadratic effect in FMT calves but not in CON. A trend for a TRT × Week interaction was observed in the liver function biomarker paraoxonase, which resulted in greater paraoxonase in FMT calves than CON at three weeks of age. Fecal microbial community analysis revealed a significant increase in the alpha-diversity between week 1 and week 5 for the FMT calves. These results suggest that early life FMT in neonatal calves has positive effects in mediating the inflammatory response and gut microbial maturation.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.