Evidence map›Paper›PMID 34573581›Full record

ArticleAnimals : an open access journal from MDPI2021

Enzymes Present in Neutrophil Extracellular Traps May Stimulate the Fibrogenic PGF

Maria Rosa Rebordão, Ana Amaral, Carina Fernandes, Elisabete Silva, Karolina Lukasik, Anna Szóstek-Mioduchowska, Pedro Pinto-Bravo, António Galvão, Dariusz J Skarzynski, Graça Ferreira-Dias

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Characterization of Myeloperoxidase in the Healthy Equine Endometrium.Animals : an open access journal from MDPI · 2023
    Article
  8. Review
  9. Article
  10. Editorial: Veterinary Reproductive Immunology.Frontiers in veterinary science · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Maria Rosa RebordãoCIISA-Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, 1300-477 Lisboa, Portugal.ORCID 0000-0002-4389-445X
Ana AmaralCIISA-Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, 1300-477 Lisboa, Portugal.ORCID 0000-0002-0075-262X
Carina FernandesCIISA-Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, 1300-477 Lisboa, Portugal.
Elisabete SilvaCIISA-Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, 1300-477 Lisboa, Portugal.ORCID 0000-0002-2332-7642
Karolina LukasikDepartment of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of PAS, 10-748 Olsztyn, Poland.ORCID 0000-0003-2476-8818
Anna Szóstek-MioduchowskaDepartment of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of PAS, 10-748 Olsztyn, Poland.
Pedro Pinto-BravoPolytechnic Institute of Coimbra, College of Agriculture, 3045-601 Coimbra, Portugal.ORCID 0000-0001-9442-7539
António GalvãoDepartment of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of PAS, 10-748 Olsztyn, Poland.
Dariusz J SkarzynskiDepartment of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of PAS, 10-748 Olsztyn, Poland.ORCID 0000-0001-9537-3560
Graça Ferreira-DiasCIISA-Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, 1300-477 Lisboa, Portugal.ORCID 0000-0003-0622-6513
University of Lisbon · PTInLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences · PLPolytechnic Institute of Coimbra · PT

Funding

Fundação para a Ciência e a Tecnologia UID/ CVT/276/2013; UIDB/00276/2020; PTDC/CVT-REP/4202/2014Narodowa Agencja Wymiany Akademickiej No. PPN/BIL/2018/1/00250/U/0001
6 · The paper itself

Abstract

Endometrosis, a fibrotic disease of mare endometrium, impairs uterine function. Prostaglandins (PG), despite modulating reproductive physiological functions, may also cause local pathological collagen deposition (fibrogenesis). We have previously shown that neutrophil extracellular traps (NETs) may also favor mare endometrosis. The aim of this study was to investigate the effect of enzymes present in NETs on PGF

Indexed as

endometriumendometrosisfibrosishorseneutrophil extracellular trapsPGF2αPGF2α receptor

Identifiers

PMID34573581
PMCPMC8469524
OpenAlexW3197755624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.