Evidence map›Paper›PMID 34573568›Full record

ArticleAnimals : an open access journal from MDPI2021

Towards Efficient Early Warning: Pathobiology of African Swine Fever Virus "Belgium 2018/1" in Domestic Pigs of Different Age Classes.

Jutta Pikalo, Marie-Eve Schoder, Julia Sehl-Ewert, Angele Breithaupt, Ann Brigitte Cay, Coline Lhoëst, Willem van Campe, Laurent Mostin, Paul Deutschmann, Hanna Roszyk and 3 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Jutta PikaloFriedrich-Loeffler-Institut, Suedufer 10, 17493 Greifswald, Germany.ORCID 0000-0003-3502-4240
Marie-Eve SchoderSciensano, Groeselenberg 99, 1180 Brussels, Belgium.
Julia Sehl-EwertFriedrich-Loeffler-Institut, Suedufer 10, 17493 Greifswald, Germany.ORCID 0000-0002-3884-1943
Angele BreithauptFriedrich-Loeffler-Institut, Suedufer 10, 17493 Greifswald, Germany.
Ann Brigitte CaySciensano, Groeselenberg 99, 1180 Brussels, Belgium.
Coline LhoëstSciensano, Groeselenberg 99, 1180 Brussels, Belgium.
Willem van CampeSciensano, Groeselenberg 99, 1180 Brussels, Belgium.
Laurent MostinSciensano, Groeselenberg 99, 1180 Brussels, Belgium.
Paul DeutschmannFriedrich-Loeffler-Institut, Suedufer 10, 17493 Greifswald, Germany.ORCID 0000-0002-2717-1358
Hanna RoszykFriedrich-Loeffler-Institut, Suedufer 10, 17493 Greifswald, Germany.
Martin BeerFriedrich-Loeffler-Institut, Suedufer 10, 17493 Greifswald, Germany.
Sandra BlomeFriedrich-Loeffler-Institut, Suedufer 10, 17493 Greifswald, Germany.ORCID 0000-0001-5465-5609
Marylène TignonSciensano, Groeselenberg 99, 1180 Brussels, Belgium.ORCID 0000-0001-9781-5289
Friedrich-Loeffler-Institut · DESciensano (Belgium) · BE

Funding

European Cooperation in Science and Technology 15116Friedrich-Loeffler-Institut, intramural funding ASF Research Network
6 · The paper itself

Abstract

African swine fever (ASF) is one of the most important and devastating viral diseases in wild boar and domestic pigs worldwide. In the absence of vaccines or treatment options, early clinical detection is crucial and requires a sound knowledge of disease characteristics. To provide practitioners and state veterinarians with detailed information, the objective of the present study was to characterize the ASF virus (ASFV) isolate "Belgium 2018/1" in subadult and weaning domestic pigs. To this end, two animal trials were performed. Trial A included eight subadult domestic pigs and trial B five weaner pigs. In general, clinical signs and pathological lesions were in line with previous studies utilizing highly virulent ASF genotype II viruses. However, in trial A, four subadult domestic pigs survived and recovered, pointing to an age-dependent outcome. The long-term fate of these survivors remains under discussion and would need further investigation.

Indexed as

African swine fever virusBelgiumclinical coursedomestic pigsvirulence

Identifiers

PMID34573568
PMCPMC8472721
OpenAlexW3192240059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.