Evidence map›Paper›PMID 34573484›Full record

ArticleAnimals : an open access journal from MDPI2021

Analytical Validation of Two Point-of-Care Assays for Serum Amyloid A Measurements in Cats.

Damián Escribano, Alba Ortín Bustillo, Luis Pardo Marín, Andrea Navarro Rabasco, Pablo Ruiz Herrera, Jose J Cerón, Asta Tvarijonaviciute

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Damián EscribanoInterdisciplinary Laboratory of Clinical Analysis, Interlab-UMU, Department of Animal Medicine & Surgery, Veterinary School, Campus Mare Nostrum, University of Murcia, 30100 Espinardo, Murcia, Spain.ORCID 0000-0001-9439-6779
Alba Ortín BustilloInterdisciplinary Laboratory of Clinical Analysis, Interlab-UMU, Department of Animal Medicine & Surgery, Veterinary School, Campus Mare Nostrum, University of Murcia, 30100 Espinardo, Murcia, Spain.
Luis Pardo MarínInterdisciplinary Laboratory of Clinical Analysis, Interlab-UMU, Department of Animal Medicine & Surgery, Veterinary School, Campus Mare Nostrum, University of Murcia, 30100 Espinardo, Murcia, Spain.
Andrea Navarro RabascoInterdisciplinary Laboratory of Clinical Analysis, Interlab-UMU, Department of Animal Medicine & Surgery, Veterinary School, Campus Mare Nostrum, University of Murcia, 30100 Espinardo, Murcia, Spain.
Pablo Ruiz HerreraInterdisciplinary Laboratory of Clinical Analysis, Interlab-UMU, Department of Animal Medicine & Surgery, Veterinary School, Campus Mare Nostrum, University of Murcia, 30100 Espinardo, Murcia, Spain.
Jose J CerónInterdisciplinary Laboratory of Clinical Analysis, Interlab-UMU, Department of Animal Medicine & Surgery, Veterinary School, Campus Mare Nostrum, University of Murcia, 30100 Espinardo, Murcia, Spain.
Asta TvarijonaviciuteInterdisciplinary Laboratory of Clinical Analysis, Interlab-UMU, Department of Animal Medicine & Surgery, Veterinary School, Campus Mare Nostrum, University of Murcia, 30100 Espinardo, Murcia, Spain.ORCID 0000-0002-5323-5001
Universidad de Murcia · ES

Funding

Fujifilm Corporation This research was supported by Fujifilm
6 · The paper itself

Abstract

Serum Amyloid A (SAA) is one of the most sensitive tests to detect inflammation in cats. In this study, two point-of-care assays for SAA measurements in cats (FUJI DRI-CHEM IMMUNO AU CARTRIDGE vf-SAA (method A), and CUBE-VET analyser (Method B), were analytically evaluated. Regarding the imprecision precision only the method A showed intra-assay and inter-assay CV < 10% at all concentrations. Both assays showed linearity with r close to 1 and the recovery were in the range of 81-112% for assay A and 85-125% for assay B and the limit of detection were 3.75 and 0.5 mg/dL for method A and B, respectively. A previously validated method for SAA quantification SAATIA; LZ-SAA (method C) was used as gold-standard to evaluate the accuracy of the assays. Significant correlations (

Indexed as

analytical validationcatinflammationpoint-of-care-assaysserum amyloid A

Identifiers

PMID34573484
PMCPMC8469286
OpenAlexW3197794596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.