Evidence map›Paper›PMID 34573407›Full record

ArticleGenes2021

Influence of

Anna Grzywacz, Krzysztof Chmielowiec, Agnieszka Boroń, Monika Michałowska-Sawczyn, Jolanta Chmielowiec, Grzegorz Trybek, Bożena Mroczek, Katarzyna Leźnicka, Paweł Cieszczyk, Jolanta Masiak

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Methylation in the Promoter Region of the Dopamine TransporterInternational journal of environmental research and public health · 2022
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Anna GrzywaczIndependent Laboratory of Health Promotion of the Pomeranian Medical University in Szczecin, 11 Chlapowskiego St., 70-204 Szczecin, Poland.ORCID 0000-0002-2633-520X
Krzysztof ChmielowiecDepartment of Hygiene and Epidemiology, Collegium Medicum, University of Zielona Góra, 28 Zyty St., 65-046 Zielona Góra, Poland.ORCID 0000-0003-4254-5466
Agnieszka BorońDepartment of Clinical and Molecular Biochemistry, Pomeranian Medical University, 72 Powstańców Wielkopolskich St., 70-111 Szczecin, Poland.ORCID 0000-0003-3574-5726
Monika Michałowska-SawczynFaculty of Physical Education, Gdansk University of Physical Education and Sport, 1 K.Górskiego St., 80-336 Gdansk, Poland.
Jolanta ChmielowiecDepartment of Hygiene and Epidemiology, Collegium Medicum, University of Zielona Góra, 28 Zyty St., 65-046 Zielona Góra, Poland.ORCID 0000-0003-3285-5313
Grzegorz TrybekDepartment of Oral Surgery, Pomeranian Medical University in Szczecin, 72 Powstańców Wlkp. St., 70-111 Szczecin, Poland.ORCID 0000-0002-3900-4901
Bożena MroczekDepartment of Human Sciences in Medicine, Pomeranian Medical University in Szczecin, 11 Chlapowskiego St., 70-204 Szczecin, Poland.
Katarzyna LeźnickaFaculty of Physical Education, Gdansk University of Physical Education and Sport, 1 K.Górskiego St., 80-336 Gdansk, Poland.
Paweł CieszczykFaculty of Physical Education, Gdansk University of Physical Education and Sport, 1 K.Górskiego St., 80-336 Gdansk, Poland.ORCID 0000-0002-7735-7580
Jolanta MasiakII Department of Psychiatry and Psychiatric Rehabilitation, Medical University of Lublin, 1 Głuska St., 20-059 Lublin, Poland.
Pomeranian Medical University · PLGdansk University of Physical Education and Sport · PLUniversity of Zielona Góra · PLMedical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the mammalian genome, DNA methylation is an epigenetic mechanism involving the transfer of a methyl group onto the C5 position of the cytosine to form 5-methylcytosine. DNA methylation regulates gene expression by recruiting proteins involved in gene repression or by inhibiting the binding of transcription factors (TFs) to DNA. As there are still many questions concerning the role of methylation in creating personality, we concentrated on searching for such associations. The research group was 100 sports male subjects (mean age = 22.88, SD = 6.35), whereas the control group included 239 healthy male volunteers matched for age (mean age = 21.69, SD = 3.39), both of European origin. The methods used in our research were as follows: DNA isolation, methylation-specific PCR, sequencing chromatophores, all conducted according to the manufacturer's procedure. To evaluate personality traits, the NEO Five-Factor Personality Inventory (NEO-FFI) and STAI Inventory were used. We observed the existence of a statistically significant correlation for all the aspects of personality covered and CpG islands' methylation. Nonetheless, we think that the tested group and the number of tested promotor islands in the

Indexed as

Athletic PerformanceAdolescentAdultAthletesCase-Control StudiesDNA MethylationDopamine Plasma Membrane Transport ProteinsGenetic Association StudiesHumansMalePolandPromoter Regions, GeneticYoung AdultDopamine Plasma Membrane Transport ProteinsSLC6A3 protein, humanathletesBDNFgenespersonalityrs10767664rs2030323

Identifiers

PMID34573407
PMCPMC8464919
OpenAlexW3200955022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.