Evidence map›Paper›PMID 34573302›Full record

ArticleGenes2021

Evolution, Expression and Meiotic Behavior of Genes Involved in Chromosome Segregation of Monotremes.

Filip Pajpach, Linda Shearwin-Whyatt, Frank Grützner

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Filip PajpachSchool of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia.ORCID 0000-0002-9357-2694
Linda Shearwin-WhyattSchool of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia.ORCID 0000-0002-4504-6534
Frank GrütznerSchool of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia.
The University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromosome segregation at mitosis and meiosis is a highly dynamic and tightly regulated process that involves a large number of components. Due to the fundamental nature of chromosome segregation, many genes involved in this process are evolutionarily highly conserved, but duplications and functional diversification has occurred in various lineages. In order to better understand the evolution of genes involved in chromosome segregation in mammals, we analyzed some of the key components in the basal mammalian lineage of egg-laying mammals. The chromosome passenger complex is a multiprotein complex central to chromosome segregation during both mitosis and meiosis. It consists of survivin, borealin, inner centromere protein, and Aurora kinase B or C. We confirm the absence of Aurora kinase C in marsupials and show its absence in both platypus and echidna, which supports the current model of the evolution of Aurora kinases. High expression of

Indexed as

Chromosome SegregationEvolution, MolecularMeiosisAnimalsAurora Kinase BAurora Kinase CCell Cycle ProteinsChromosomal Proteins, Non-HistoneCohesinsPlatypusAurora Kinase BAurora Kinase CCell Cycle ProteinsChromosomal Proteins, Non-HistoneCohesinsAurora kinasechromosome passenger complexcohesinmeiosismonotremesex chromosome multiple

Identifiers

PMID34573302
PMCPMC8470780
OpenAlexW3195792491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.