ArticleBrain sciences2021
A Therapeutic Matrix: Virtual Reality as a Clinical Tool for Spinal Cord Injury-Induced Neuropathic Pain.
Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Linking Embodiment, Simulator Sickness, and EEG Activity During XR-BCI Use: A Single-Participant Case Study.Life (Basel, Switzerland) · 2026Article
- Development of the SCI-BodyMap-Measuring Mental Body Representations in Adults With Spinal Cord Injury: Protocol for Item Generation, Reliability, and Validity Testing.JMIR research protocols · 2025Article
- Chronic Pain Modulates Empathic Responses in People with Spinal Cord Injury.Journal of clinical medicine · 2025Article
- Applying a Virtual Art Therapy System Based on the Michelangelo Effect in Patients with Spinal Cord Injury.Sensors (Basel, Switzerland) · 2025Article
- Virtual Reality Interventions for Spinal Cord Injury-Related Neuropathic Pain: A Comprehensive Scoping Review of Multidimensional Outcomes.Journal of pain research · 2025Review
- The Role of Virtual Reality in Chronic Pain and Loneliness: Narrative Review.Journal of medical extended reality · 2025Review
- Immersive virtual reality for chronic neuropathic pain after spinal cord injury: a pilot, randomized, controlled trial.Pain reports · 2024Article
- Sensorimotor Uncertainty of Immersive Virtual Reality Environments for People in Pain: Scoping Review.Brain sciences · 2023Article
- Do Individuals with Spinal Cord Injury Benefit from Semi-Immersive Virtual Reality Cognitive Training? Preliminary Results from an Exploratory Study on an Underestimated Problem.Brain sciences · 2023Article
- Role of Immersive Virtual Reality in Motor Behaviour Decision-Making in Chronic Pain Patients.Brain sciences · 2023Review
- Feasibility of using remotely delivered Spring Forest Qigong to reduce neuropathic pain in adults with spinal cord injury: a pilot study.Frontiers in physiology · 2023Article
- The role of virtual reality as adjunctive therapy to spinal cord stimulation in chronic pain: A feasible concept?Frontiers in pain research (Lausanne, Switzerland) · 2023Review
- Integrated Neuroregenerative Techniques for Plasticity of the Injured Spinal Cord.Biomedicines · 2022Article
- Future Treatment of Neuropathic Pain in Spinal Cord Injury: The Challenges of Nanomedicine, Supplements or Opportunities?Biomedicines · 2022Article
- Exoskeletons for Mobility after Spinal Cord Injury: A Personalized Embodied Approach.Journal of personalized medicine · 2022Article
- The Role of Body in Brain Plasticity.Brain sciences · 2022Article
- Rethinking the Body in the Brain after Spinal Cord Injury.Journal of clinical medicine · 2022Article
- The role of arousal and motivation in emotional conflict resolution: Implications for spinal cord injury.Frontiers in human neuroscience · 2022Article
- Embodiment Comfort Levels During Motor Imagery Training Combined With Immersive Virtual Reality in a Spinal Cord Injury Patient.Frontiers in human neuroscience · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Neuropathic pain (NP) is a chronic, debilitating, and resistant form of pain. The onset rate of NP following spinal cord injuries (SCI) is high and may reduce the quality of life more than the sensorimotor loss itself. The long-term ineffectiveness of current treatments in managing symptoms and counteracting maladaptive plasticity highlights the need to find alternative therapeutic approaches. Virtual reality (VR) is possibly the best way to administer the specific illusory or reality-like experience and promote behavioral responses that may be effective in mitigating the effects of long-established NP. This approach aims to promote a more systematic adoption of VR-related techniques in pain research and management procedures, highlighting the encouraging preliminary results in SCI. We suggest that the multisensory modulation of the sense of agency and ownership by residual body signals may produce positive responses in cases of brain-body disconnection. First, we focus on the transversal role embodiment and how multisensory and environmental or artificial stimuli modulate illusory sensations of bodily presence and ownership. Then, we present a brief overview of the use of VR in healthcare and pain management. Finally, we discus research experiences which used VR in patients with SCI to treating NP, including the most recent combinations of VR with further stimulation techniques.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.