Evidence map›Paper›PMID 34573219›Full record

ArticleBrain sciences2021

Primary Progressive Aphasia: Use of Graphical Markers for an Early and Differential Diagnosis.

Alexandra Plonka, Aurélie Mouton, Joël Macoir, Thi-Mai Tran, Alexandre Derremaux, Philippe Robert, Valeria Manera, Auriane Gros

Abstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandra PlonkaDépartement d'Orthophonie de Nice, Faculté de Médecine, Université Côte d'Azur, 06000 Nice, France.
Aurélie MoutonDépartement d'Orthophonie de Nice, Faculté de Médecine, Université Côte d'Azur, 06000 Nice, France.
Joël MacoirDépartement de Réadaptation, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada.ORCID 0000-0002-6661-430X
Thi-Mai TranLaboratoire STL, UMR 8163, Département d'Orthophonie, UFR3S, Université de Lille, 59000 Lille, France.
Alexandre DerremauxLaboratoire CoBTeK (Cognition Behaviour Technology), Université Côte d'Azur, 06000 Nice, France.
Philippe RobertDépartement d'Orthophonie de Nice, Faculté de Médecine, Université Côte d'Azur, 06000 Nice, France.
Valeria ManeraLaboratoire CoBTeK (Cognition Behaviour Technology), Université Côte d'Azur, 06000 Nice, France.
Auriane GrosDépartement d'Orthophonie de Nice, Faculté de Médecine, Université Côte d'Azur, 06000 Nice, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary progressive aphasia (PPA) brings together neurodegenerative pathologies whose main characteristic is to start with a progressive language disorder. PPA diagnosis is often delayed in non-specialised clinical settings. With the technologies' development, new writing parameters can be extracted, such as the writing pressure on a touch pad. Despite some studies having highlighted differences between patients with typical Alzheimer's disease (AD) and healthy controls, writing parameters in PPAs are understudied. The objective was to verify if the writing pressure in different linguistic and non-linguistic tasks can differentiate patients with PPA from patients with AD and healthy subjects. Patients with PPA (n = 32), patients with AD (n = 22) and healthy controls (n = 26) were included in this study. They performed a set of handwriting tasks on an iPad

Indexed as

Alzheimer’s diseasedifferential diagnosisgraphical markersgraphical parametersprimary progressive aphasiawriting pressure

Identifiers

PMID34573219
PMCPMC8464890

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.