ArticleBrain sciences2021
Comprehensive Evaluation of Factors Affecting Tremor Relapse after MRgFUS Thalamotomy: A Case-Control Study.
Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Tremor Recurrence in MR-Guided Focused Ultrasound Thalamotomy for Essential Tremor: DBS vs. Re-lesion.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
- The Results of a 12-Month Open-Label Follow-Up Study with MRI Monitoring of Patients with Parkinson's Disease After MRI-Guided FUS.Journal of clinical medicine · 2025Article
- Fibrinogen is the key factor associated with tremor relief and recurrence after magnetic resonance-guided focused ultrasound thalamotomy.Clinical parkinsonism & related disorders · 2025Article
- Radiomic signatures from postprocedural MRI thalamotomy lesion can predict long-term clinical outcome in patients with tremor after MRgFUS: a pilot study.Frontiers in radiology · 2025Article
- Unilateral focused ultrasound thalamotomy for tremor-dominant Parkinson's disease: blinded evaluation and imaging correlation.Brain communications · 2025Article
- Clinical neurophysiology in the treatment of movement disorders: IFCN handbook chapter.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Review
- [Unilateral thalamotomy with high intensity focal ultrasound in patients with refractory essential tremor: a comparative study between patients under and over 70 years of age].Revista de neurologia · 2024Article
- Early re-emerging tremor after MRgFUS thalamotomy: case-control analysis of procedural and imaging features.Frontiers in neurology · 2024Article
- Radiofrequency thalamotomy for tremor produces focused and predictable lesions shown on magnetic resonance images.Brain communications · 2023Article
- Magnetic Resonance-guided Focused Ultrasound thalamotomy for refractory neuropathic pain: a systematic review and critical appraisal of current knowledge.Therapeutic advances in neurological disorders · 2023Review
- Evaluation of Cerebral Volume Changes in Patients with Tremor Treated by MRgFUS Thalamotomy.Life (Basel, Switzerland) · 2022Article
- Cerebello-Thalamo-Cortical MR Spectroscopy in Patients with Essential Tremor Undergoing MRgFUS Thalamotomy: A Pilot Study.Life (Basel, Switzerland) · 2022Article
- Neurotrophins as Therapeutic Agents for Parkinson's Disease; New Chances From Focused Ultrasound?Frontiers in neuroscience · 2022Review
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify possible relevant factors contributing to tremor relapse after MRgFUS thalamotomy in patients with essential tremor (ET) and Parkinson's disease (PD).
methodsWe identified patients with tremor relapse from a series of 79 treatments in a single institution. The demographic and clinical characteristics of the study group patients were compared to those of patients who did not relapse in the same follow-up period. Imaging and procedural factors were compared using a control group matched for clinical and demographic characteristics.
resultsConcerning clinical and demographic characteristics, we did not find statistically significant differences in gender and age. Seventy-three percent of patients with tremor relapse were Parkinson's disease patients. Using MRI, we found larger thalamotomy lesions at the 1-year follow-up in the control group with stable outcomes, compared to patients with tremor relapse. In the tractography evaluation, we found a more frequent eccentric position of the DRTt in patients with tremor relapse.
conclusionsThe most relevant determining factors for tremor relapse after MRgFUS thalamotomy appear to be tremor from Parkinson's disease and inaccurate thalamic targeting. Size of the thalamotomy lesion can also influence the outcome of treatment.
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