ArticleBrain sciences2021
Risk of Developing Epilepsy after Autoimmune Encephalitis.
Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Seizure outcome-related factors in autoimmune encephalitis: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Does classical semiology ("5As") predict post-operative seizure outcome in patients with temporal lobe epilepsy?Epileptic disorders : international epilepsy journal with videotape · 2026Article
- Predicting epilepsy after new onset refractory status epilepticus due to autoimmune encephalitis: The DAME score.Epilepsia · 2026Article
- WONOEP XVII appraisal: The immunopathogenesis of epilepsy.Epilepsia · 2026Review
- Clinical Description and Acute Outcomes of Cryptogenic Encephalitis in the Intensive Care Unit.Neurocritical care · 2025Article
- Imaging biomarkers in antibody-mediated autoimmune encephalitis.Quantitative imaging in medicine and surgery · 2025Article
- Prognostic factors underlying the development of drug-resistant epilepsy in patients with autoimmune encephalitis: a retrospective cohort study.Journal of neurology · 2024Observational
- Virus-Induced Epilepsy vs. Epilepsy Patients Acquiring Viral Infection: Unravelling the Complex Relationship for Precision Treatment.International journal of molecular sciences · 2024Review
- Epilepsy, Immunity and Neuropsychiatric Disorders.Current neuropharmacology · 2023Review
- Article
- Acute Symptomatic Seizures and Risk of Epilepsy in Autoimmune Encephalitis: A Retrospective Cohort Study.Frontiers in immunology · 2022Article
- Role of responsive neurostimulation and immunotherapy in refractory epilepsy due to autoimmune encephalitis: A case report.Frontiers in neurology · 2022Article
- Factors Influencing the Withdrawal of Antiepileptic Drugs in Adult Patients with Symptomatic Seizures Secondary to Neuronal Surface Antibodies-Associated Autoimmune Encephalitis.Journal of inflammation research · 2022Article
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute symptomatic seizures (ASS) are a common manifestation of autoimmune encephalitis (AE), but the risk of developing epilepsy as a sequela of AE remains unknown, and factors predisposing the development of epilepsy have not been fully identified.
objectiveTo assess the risk of developing epilepsy in AE and study related risk factors. MATERIALS AND
methodsThis was a retrospective single centre study including patients diagnosed with AE according to criteria described by Graus et al., with a minimum follow-up of 12 months after AE resolution. The sample was divided according to whether patients developed epilepsy or not.
resultsA total of 19 patients were included; 3 (15.8%) had AE with intracellular antibodies, 9 (47.4%) with extracellular antibodies, and 7 (36.8%) were seronegative. During follow-up, 3 patients (15.8%) died, 4 (21.1%) presented relapses of AE, and 11 (57.89%) developed epilepsy. There was a significant association between the development of epilepsy and the presence of hippocampal atrophy in control brain magnetic resonance imaging (MRI) (
conclusionsHippocampal atrophy in neuroimaging, IED on EEG during follow-up, and immunotherapy delay could be predictors of the development of epilepsy in patients with AE.
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