Evidence map›Paper›PMID 34573201›Full record

ArticleBrain sciences2021

Comparing Pathological Risk Factors for Dementia between Cognitively Normal Japanese and Americans.

Chendi Cui, Aya Higashiyama, Brian J Lopresti, Masafumi Ihara, Howard J Aizenstein, Makoto Watanabe, Yuefang Chang, Chikage Kakuta, Zheming Yu, Chester A Mathis and 8 more

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 2 countries.

Chendi CuiDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Aya HigashiyamaDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan.
Brian J LoprestiDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Masafumi IharaDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan.ORCID 0000-0002-7102-4048
Howard J AizensteinDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Makoto WatanabeDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan.
Yuefang ChangDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Chikage KakutaDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan.
Zheming YuDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Chester A MathisDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Yoshihiro KokuboDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan.
Tetsuya FukudaDepartment of Radiology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan.
Victor L VillemagneDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA.
William E KlunkDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Oscar L LopezDepartment of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Lewis H KullerDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Yoshihiro MiyamotoDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan.
Akira SekikawaDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0002-7197-6321
University of Pittsburgh · USNational Cerebral and Cardiovascular Center · JPWakayama Medical University · JP

Funding

Omega-3, isoflavones & amyloid deposition in cognitively normal elderly JapaneseRF1AG051615 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SEKIKAWA, AKIRA · 2016 to 2016
$1.8M
NIA NIH HHS RF1 AG051615
6 · The paper itself

Abstract

The Alzheimer's Disease Neuroimaging Initiative showed that Japanese had significantly lower brain Aβ burden than Americans among a cognitively normal population. This cross-sectional study aimed to compare vascular disease burden, Aβ burden, and neurodegeneration between cognitively normal elderly Japanese and Americans. Japanese and American participants were matched for age (±4-year-old), sex, and Apolipoprotein E (

Indexed as

amyloid PET imagingbiomarkerJapanesemagnetic resonance imagingneuroimaging

Identifiers

PMID34573201
PMCPMC8469296
OpenAlexW3197169564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.