Evidence map›Paper›PMID 34573136›Full record

ArticleBrain sciences2021

Intermittent Theta Burst Stimulation to the Primary Motor Cortex Reduces Cortical Inhibition: A TMS-EEG Study.

Zhongfei Bai, Jiaqi Zhang, Kenneth N K Fong

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Zhongfei BaiDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong.ORCID 0000-0001-9800-7080
Jiaqi ZhangDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong.ORCID 0000-0002-4656-1909
Kenneth N K FongDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong.ORCID 0000-0001-5909-4847
Hong Kong Polytechnic University · HK

Funding

General Research Fund, Research Grants Council, University Grants Committee, Hong Kong 15105919MShanghai Sailing Program, China 20YF1445100
6 · The paper itself

Abstract

introductionThe aim of this study was to reveal the effects of intermittent theta burst stimulation (iTBS) in modulating cortical networks using transcranial magnetic stimulation and electroencephalography (TMS-EEG) recording.

methodsEighteen young adults participated in our study and received iTBS to the primary motor cortex (M1), supplementary motor area, and the primary visual cortex in three separate sessions. A finger tapping task and ipsilateral single-pulse TMS-EEG recording for the M1 were administrated before and after iTBS in each session. The effects of iTBS in motor performance and TMS-evoked potentials (TEPs) were investigated.

resultsThe results showed that iTBS to the M1, but not supplementary motor area or the primary visual cortex, significantly reduced the N100 amplitude of M1 TEPs in bilateral hemispheres (

conclusionOur study confirmed the local and remote after-effects of iTBS in reducing cortical inhibition in the M1. TMS-induced oscillations after iTBS for changed cortical excitability in patients with various neurological and psychiatric conditions are worth further exploration.

Indexed as

cortical inhibitionprimary motor cortexTMS-evoked potentialstranscranial magnetic stimulation

Identifiers

PMID34573136
PMCPMC8472376
OpenAlexW3195454292

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.