ReviewAntioxidants (Basel, Switzerland)2021
Management of Feline Hyperthyroidism and the Need to Prevent Oxidative Stress: What Can We Learn from Human Research?
Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Haematological Tracking of Thyroid Status During Methimazole Therapy and After Treatment Interruption in Hyperthyroid Cats: A Prospective Longitudinal Cohort Study.Veterinary sciences · 2026Article
- A predictive algorithm for the optimal daily dosage of thiamazole to control cats with hyperthyroidism.Journal of veterinary internal medicine · 2026Article
- Capsiate ameliorates secondary hyperparathyroidism by improving insulin sensitivity and inhibiting angiogenesis.Journal of cellular and molecular medicine · 2024Article
- Elucidating the role of phytocompounds fromIn silico pharmacology · 2024Article
- Dietary Antioxidants and Chronic Diseases.Antioxidants (Basel, Switzerland) · 2023Article
- Aging-Associated Thyroid Dysfunction Contributes to Oxidative Stress and Worsened Functional Outcomes Following Traumatic Brain Injury.Antioxidants (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Feline hyperthyroidism is a clinical syndrome related to an excessive production of thyroid hormones, and it is considered as a spontaneous animal model for human thyrotoxicosis. Many shared features between the feline and the human disease have been identified so far, including pathogenesis, clinical signs, and treatment options. Although methimazole is considered the first-choice drug in both species, several side effects have been described. Furthermore, methimazole could interfere with the oxidative status, already perturbated by the disease. It has been reported in humans that dietary management, mainly through antioxidant supplementation, could mitigate this oxidative burden. The purpose of the review is to describe current therapeutic options in the course of feline hyperthyroidism and to summarize the state of the art relationship between dietary antioxidants administration and the reduction of methimazole side-effects in humans to support the use of this approach also in cats.
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Registered trials
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